Enter intramuscularly into the upper outer quadrant of the gluteus muscle or external surface of the thigh. Do not administer the drug intravenously!
Before the injection, the ampoule with the drug is kept for 2 hours at room temperature (20 ± 2) ° C. Opening of ampoules and the procedure of administration are carried out with strict adherence to aseptic and antiseptic rules. To prevent the formation of foam, the drug is drawn into the syringe with a needle with a wide lumen.
The drug in the opened ampoule is not subject to storage.
The dose of immunoglobulin and the frequency of its administration depend on the indications for use.
Prevention of hepatitis A
The drug is administered once in doses: children from 1 to 6 years - 0.75 ml; 7-10 years - 1.5 ml; older than 10 years and adults - 3.0 ml.
Repeated administration of immunoglobulin if necessary hepatitis A is not shown before 2 months later.
Prevention of measles
The drug is administered once from 3 months of age not with measles and not vaccinated against this infection, no later than 6 days after contact with the patient.
The dose of the drug to children (1.5 or 3.0 ml) is set depending on the condition health and time that has passed since the moment of contact.Adults, and also children, in contact with mixed infections, the drug is administered in a dose of 3 ml.
Prevention of influenza
The drug is administered once in doses: for children under 2 years - 1.5 ml; from 2 to 7 years - 3.0 ml; older than 7 years and adults - 4,5-6,0 ml. In the treatment of severe forms of influenza, repeated (24-48 hours) administration of immunoglobulin at the same dosage is indicated.
Prophylaxis of pertussis
Not sick with pertussis children the drug is administered twice with an interval of 24 hours in a single dose of 3 ml at the earliest possible time after contact with the patient.
Prevention of meningococcal infection
The drug is administered once to children aged from 6 months to 7 years, no later than 7 day after contact with the patient with a generalized form of meningococcal infection in doses of 1.5 ml (children under 3 years old) and 3 ml (children over 3 years old).
Prevention of poliomyelitis
The drug is administered once in a dose of 3.0-6.0 ml of non-grafted or inferiorly grafted poliomyelitis vaccine to children at the earliest possible time after contact with the patient with a paralytic form of poliomyelitis.
Treatment of hypo- and agammaglobulinemia in children
The drug is administered in a dose of 1.0 ml per kg of body weight; The calculated dose can be entered into 2-3 doses at an interval of 24 hours.The subsequent administration of immunoglobulin is carried out according to the indications no earlier than 1 month later.
Increase of resistance of the organism in the period of reconvalescence of acute infectious diseases with prolonged course and with chronic and protracted pneumonia
The drug is administered in a single dose of 0.15-0.2 ml per 1 kg of body weight. Multiplicity of administration (up to 4 injections) is determined by the doctor; intervals between injections are 2-3 days.