Clenzite - instructions for use, dose, side effects, contraindications

Excipients: disodium edetate, carbomer 940 (carbopol 940), propylene glycol, methyl parahydroxybenzoate, phenoxyethanol, poloxamer 407, sodium hydroxide, purified water.

Description:Homogeneous gel of white color.

Pharmacotherapeutic group:Treatment for acne

ATX: & nbsp

D.10.A.D. Preparations for the treatment of acne for external use containing retinoids

D.10.A.D.03 Adapalen

Pharmacodynamics:

Adapalene is a retinoid metabolite, has a comedonolytic and anti-inflammatory activity, normalizes the processes of keratinization and epidermal differentiation. The mechanism of action of adapalene is based on interaction with specific γ-receptors of skin epidermal cells. As a result of the action of adapalene, in particular, the "cohesion" of epithelial cells in the mouth of the sebaceous-hair follicle decreases and the preconditions for the formation of micro-comedones decrease. Adapalen has anti-inflammatory effect in vivo and in vitro, Influencing factors of inflammation by inhibiting migration of leukocytes in the focus of inflammation and the metabolism of arachidonic acid.

Pharmacokinetics:

Absorption of adapalene through the skin is very low (about 4% of the applied dose). Excretion from the body occurs mainly through bile.

Indications:

Acne.

Contraindications:

Hypersensitivity to one of the ingredients of the drug, pregnancy, lactation.

Carefully:

Dermatitis, eczema.

Pregnancy and lactation:

It is not recommended to use the drug during pregnancy and breastfeeding.

Dosing and Administration:

Outwardly. Before applying the Clenzit gel, it is necessary to clean and dry the skin of the face. With a gentle touch, apply the gel evenly to the affected area once a day before going to bed to clean, dry skin, avoiding getting the product into the eyes and lips. The therapeutic effect develops after 4-8 weeks of treatment, a persistent improvement after 3 months of treatment.

In some cases, due to short-term skin irritation, treatment can be suspended until the symptoms of irritation disappear.

Repeated treatment is possible after consultation with a doctor.

Side effects:

Skin irritation (treatment should be stopped until skin irritation disappears or frequency of application is reduced).

Overdose:

Overdose is unlikely.

Interaction:

Since the drug does not interact with oxygen and does not break down under the influence of light, it is possible to simultaneously treat acne with drugs such as clindamycin phosphate or benzoyl peroxide.

Special instructions:

Avoid getting the gel in the eyes and on the lips.

If you accidentally get the drug on the mucous eyes, mouth or nose, rinse thoroughly with warm water.

Avoid direct sunlight. may cause skin irritation. Treatment can be continued if the solar exposure is minimized (using sunglasses and hats).

It is not recommended simultaneous use of cosmetics with drying and irritating effect on the skin (for example, perfume or alcohol-containing funds).

Adapalene, applied to the skin in the evening, can be combined with drugs for the treatment of blackheads, applied in the morning.

Form release / dosage:Gel for external use 0,1%.

Packaging:For 15 g and 30 g in lacquered aluminum tubes, having a nozzle with a closed end, with a lid having a point for piercing. One tube together with the instruction for use is placed in a cardboard box.

Storage conditions:

In the dark place at a temperature of no higher than 25 ° C. Do not freeze. Keep out of the reach of children.

Shelf life:3 years. Do not use after expiry date.

Terms of leave from pharmacies:Without recipe

Registration number:LSR-005106/07

Date of registration:24.12.2007 / 08.11.2017

Expiration Date:Unlimited

The owner of the registration certificate:Glenmark Pharmaceuticals Co., Ltd.Glenmark Pharmaceuticals Co., Ltd. India

Manufacturer: & nbsp

GLENMARK PHARMACEUTICALS, Ltd. India

Representation: & nbspGLENMARK PHARMACEUTICALS LTD. GLENMARK PHARMACEUTICALS LTD. India

Information update date: & nbsp25.01.2018

Illustrated instructions

Instructions

Clenzite (Klenzit)