Kokarboksilazu injected intramuscularly or intravenously (struino or drip). The contents of the ampoule (50 mg) are dissolved immediately before injection into 2 ml of water for injection. With intravenous jet injection, the volume is adjusted to 10-20 ml, with dropwise administration - up to 200-400 ml, adding a 0.9% solution of sodium chloride or a 5% solution of dextrose (glucose).
With violations of the heart rate: 100-200 mg per day for 15-30 days. In chronic heart failure: 50 mg 2 hours before the use of digitalis preparations 2-3 times a day.
In diabetes (ketoacidosis, coma), the daily dose is 100 mg.
In acute renal and hepatic insufficiency intravenously injected 100-150 mg 3 times a day or drip (previously dissolved in a 5% solution of dextrose (glucose)) for 100-150 mg per day.
With peripheral neuritis, intramuscularly administered at a dose of 50-100 mg per day for 1-1.5 months.
Children are given intramuscularly, intravenously (drip or jet). Depending on the severity of the condition and clinical symptoms, it is prescribed from 25 to 50 mg per day. The course of treatment is from 3-7 to 15-30 days. The newborn is injected intravenously (slowly) 10 mg per 1 kg of body weight once a day.