Kokarboksilazu injected intramuscularly or intravenously (struino or drip). The contents of the ampoule (50 mg) are dissolved immediately before injection into 2 ml of water for injection. With intravenous injection, the volume is adjusted to 10-20 ml, with dropwise administration up to 200-400 ml, adding a 0.9% solution of sodium chloride or a solution of dextrose.
Adults
With violations of the heart rate: 100-200 mg per day for 15-30 days.
For chronic heart failure: 50 mg for 2 hours before the use of digitalis preparations 2-3 times a day.
In diabetes (ketoacidosis, coma): the daily dose is 100 mg.
In acute renal and hepatic insufficiency: intravenously strontium 100-150 mg 3 times a day or drip (previously dissolved in 5 % solution of dextrose) at 100-150 mg per day.
With peripheral neuritis: intramuscularly at 50-100 mg per day for 1-1.5 months.
Children - in / m, in / in (drip or jet): depending on the severity and clinical symptoms - 25-50 mg / day. The course of treatment is from 3-7 to 15 days. The newborn is injected / in slowly -10 mg / kg 1 time per day.