Kokarboksilazu injected intramuscularly or intravenously (struino or drip).
If heart rhythm disturbances are prescribed, 100-200 mg / day for 15-30 days.
In chronic heart failure: 50 mg 2 hours before the use of digitalis preparations 2-3 times a day.
In diabetes (ketoacidosis, coma), the daily dose is 100 mg.
In acute renal and hepatic insufficiency intravenously injected 100-150 mg 3 times a day or drip (previously dissolved in a 5% solution of dextrose (glucose)) at 100-150 mg / day.
With peripheral neuritis, intramuscularly administered at a dose of 50-100 mg / day for 1-1.5 months.
Children injected intramuscularly, intravenously (by drip or jet). Depending on the severity and clinical symptoms appointed from 25 to 50 mg / day. The course of treatment is from 3-7 to 15-30 days. The newborn is administered intravenously (slowly) 10 mg / kg once a day.
Preparation of solutions
For intramuscular administration, the contents of the ampoule (50 mg) are dissolved immediately before administration to 2 ml of water for injection.
For intravenous fluid administration, the volume of the solution is adjusted to 10-20 ml, for drip administration - up to 200-400 ml, adding a 0.9% solution of sodium chloride or a solution of dextrose.