Possible side effects with Maninil® 1.75 are given below in the descending incidence frequency: often (> 1/100, <1/10), infrequently (> 1/1000, <1/100), rarely (> 1/10000 , <1/1000), very rarely (<1/10000), including individual messages.
Disorders from the metabolism and nutrition:
Often: hypoglycemia (hunger, hyperthermia, tachycardia, drowsiness, weakness, skin moisture, movement coordination disorder, tremor, general anxiety, fear, headache, transient neurological disorders (eg, visual and speech disorders, paresis or paralysis, or altered perceptions sensations), weight gain;
Disorders from the gastrointestinal tract:
Infrequently: nausea, a feeling of heaviness in the stomach, belching, vomiting, abdominal pain, diarrhea, a "metallic" taste in the mouth;
Violation of the liver and biliary tract:
Rarely: a temporary increase in the activity of "hepatic" enzymes, intrahepatic cholestasis, hepatitis;
Immune system disorders:
Infrequently: itching, hives, purpura, petechiae, increased photosensitivity.
Highly rarely: generalized allergic reactions accompanied by skin rashes, arthralgia, fever, proteinuria and jaundice; allergic vasculitis; anaphylactic shock.
Violations from the blood and lymphatic system:
Rarely: thrombocytopenia;
Rarely: leukopenia, erythropenia, agranulocytosis;
In a few cases: pancytopenia, hemolytic anemia.
Other:
Rarely: visual impairment and accommodation disorders, diuresis intensification, transient proteinuria, hyponatremia, "antabuse effect" (disulfiramoid-like reaction) with alcohol intake (most common signs of effect: nausea, vomiting, abdominal pain, fever of the facial and upper body, tachycardia; dizziness, headache). Cross-allergy to probenecid, sulfonylureas, sulfonamides, diuretic agents containing a sulfonamide group in the molecule.