In rare cases, there is nausea, a metallic taste in the mouth, anorexia, epigastric pain, vomiting, diarrhea, headache, dizziness, as well as local skin reactions such as hives and itching.
Very rarely - depression.
With prolonged treatment with large doses, there may be leukopenia, peripheral neuropathies.
Very rare and reversible cases of pancreatitis are described.
It is possible to stain urine in a reddish-brown color due to the presence of pigments associated with Metronidazole metabolism.
From the digestive system: diarrhea, decreased appetite, nausea, vomiting, intestinal colic, constipation, "metallic" taste in the mouth, dry mouth, glossitis, stomatitis, pancreatitis.
From the nervous system: dizziness, impaired coordination of movements, ataxia, confusion, irritability, depression, increased excitability, weakness, insomnia, headache, convulsions, hallucinations, peripheral neuropathy.
Allergic reactions: urticaria, skin rash, skin hyperemia, nasal congestion, fever, arthralgia.
From the urinary system: dysuria, cystitis, polyuria, urinary incontinence, candidiasis, staining of urine in red-brown color.
Other: neutropenia, leukopenia, flattening of the T wave on the electrocardiogram.