Sodium chloride solution is complex [Potassium chloride + Calcium chloride + Sodium chloride] (Solutio Natrii chloridi composita (Kalii chloridum + Calcii chloridum + Natrii chloridum))

Pharmacodynamics Pharmacokinetics Indications Carefully Contraindications Dosing and Administration Side effects
Read on
Clinical and pharmacological group: & nbsp

Substitutes for plasma and other blood components

Regulators of water-electrolyte balance and KHS

Included in the formulation
  • Ringer's solution
    solution in / in d / infusion 
    MOSFARM, LLC    
  • Ringer's solution
    solution in / in d / infusion 
    Hemofarm AD     Serbia
  • Ringer's solution for infusions
    solution in / in d / infusion 
    SAKHAMEDPROM, SUE     Russia
  • Ringer
    solution in / in d / infusion 
    RESTER, CJSC     Russia
  • Ringer
    solution in / in d / infusion 
    FIRM MEDPOLIMER, JSC     Russia
  • Ringer
    solution in / in d / infusion 
    GROTEKS, LLC     Russia
  • Ringer's solution
    solution in / in d / infusion 
    ESKOM NPK, OAO     Russia
  • Ringer's solution
    solution in / in d / infusion 
    KRASFARMA, JSC     Russia
  • Ringer's solution
    solution in / in d / infusion 
    BIOSINTEZ, PAO     Russia
  • Ringer's solution
    solution in / in d / infusion 
    MEDSINTEZ FACTORY, LTD.     Russia
  • Ringer's solution
    solution d / infusion 
    ALIUM PFK, LLC     Russia
    • Included in the list (Order of the Government of the Russian Federation No. 2782-r of 30.12.2014):

    VED

    АТХ:

    B.05.B.B   Solutions affecting the water-electrolyte balance

    B.05.B.B.01   Electrolytes

    Pharmacodynamics:

    It has detoxification and rehydration action, stabilizes the electrolyte composition of blood plasma.

    Pharmacokinetics:

    After intravenous administration for 30-40 minutes leaves the bloodstream, accumulating in the extravasal space.

    Indications:

    Used for rehydration and as a plasma substitute for frostbites, shock, burns, diarrhea and prolonged vomiting. Used for peritonitis, intestinal obstruction, dehydration state, metabolic alkalosis.

    ICD-10

    IV.E70-E90.E86   Reduction of the volume of the liquid

    IV.E70-E90.E87.3   Alkalosis

    XI.K65-K67.K65.0   Acute peritonitis

    XVIII.R50-R69.R57.0   Cardiogenic shock

    XVIII.R50-R69.R57.1   Hypovolemic shock

    XVIII.R50-R69.R57.8   Other types of shock

    XVIII.R50-R69.R58   Bleeding, not elsewhere classified

    XIX.T20-T32.T30   Thermal and chemical burns, unspecified

    XIX.T33-T35.T33   Surface frostbite

    XIX.T79.T79.4   Traumatic shock

    Contraindications:

    Hypernatremia, hyperchloremia, pulmonary and brain edema, acidosis, chronic renal failure, individual intolerance.

    Carefully:

    Pregnancy and lactation.

    Pregnancy and lactation:

    Recommendations for FDA - Category C. It is used with caution in pregnancy and lactation in cases where the expected effect exceeds the risk to the fetus and newborn.

    Dosing and Administration:

    Use in children

    Intravenously drip. The daily dose is 5-10 ml / kg of weight at a rate of 30-60 drops per minute.

    Adults

    Intravenously drip, at a rate of 60-80 drops per minute.

    The highest daily dose: 50 ml / kg.

    Side effects:

    Allergic reactions.

    Overdose:

    Cases of overdose are not described.

    Treatment is symptomatic.
    Interaction:

    Enhances the toxic effects of cardiac glycosides.

    With simultaneous application with potassium-sparing diuretics, the development of hyperkalemia is possible.

    When used simultaneously with non-steroidal anti-inflammatory drugs, androgens, estrogens, anabolic steroids, vasodilators, ganglion blockers and mineralocorticoids, the risk of hypernatremia increases.

    Special instructions:

    In connection with the rapid exit from the vascular bed, the drug is used only for the purpose short-term replenishment of the circulating blood volume.

    Instructions
    Up