Ringer's solution - instructions for use, doses, side effects, contraindications

Pharmacokinetics:When used as a means of replenishment of the central central blood flow, because of the rapid exit from the bloodstream into the extravasal space, the effect persists for only 30-40 minutes (in connection with which the solution is only suitable for short-term replenishment of the central central rifle).

Indications:

As plazmozameschayuschego means in the absence of the need for compensation of red blood cells, incl. shock, collapse, burns, prolonged vomiting, frostbite, diarrhea. For correction of water and electrolyte balnea with acute diffuse peritonitis and intestinal obstruction, intestinal fistula; dehydration of various etiologies.

Contraindications:

Hypersensitivity to drug components, hypernatremia, hyperchloremia, acidosis, hypervolemia, chronic heart failure, cerebral edema, pulmonary edema, chronic renal failure, concomitant therapy with glucocorticosteroids.

Carefully:not described

Pregnancy and lactation:

During pregnancy, apply in those cases when the expected benefit of the mother's day exceeds the possible risk of the fetal day. It should refrain from breastfeeding during the period of use of the drug because of the lack of relevant clinical data.

Dosing and Administration:

Intravenously drip, at a speed of 60-80 cap / min, or jet. The daily dose for adults is 5-20 ml / kg, if necessary, can be increased to 30-50 ml / kg. The daily dose for children is 5-10 ml / kg, the rate of administration is 30-60 cap / min, with shock dehydration initially injected with 20-30 ml / kg. The course of treatment is 3-5 days.

Side effects:

Hyperhydration, gnucopotomy; allergic reactions.

Overdose:not described

Interaction:

It is possible to increase the delay of sodium in the body with the simultaneous administration of the following medicines: estrogens, nonsteroidal anti-inflammatory drugs, androgens, anabolic hormones, corticotropin, mineralocorticoids, vasodilators or ganglion blockers. When taking with Kalnesberegayuschimi diuretics, angiotensin-converting enzyme (ACE) inhibitors and potassium preparations, the risk of hyperkalemia increases.In combination with cardiac glycosides, the likelihood of their toxic effects increases.

Special instructions:

In the case of rapid introduction of a large volume, it is necessary to control the acid-base state and the level of electrolytes. A change in the pH of the blood (acidification) leads to redistribution of the ions K⁺ (lowering the pH leads to an increase in the content of ions K⁺ in the blood serum).

With prolonged use, it is necessary to monitor the concentration of electrolytes in plasma and daily diuresis.

Due to the high level of chloride ions, long-term use of the drug is not recommended.

Effect on the ability to drive transp. cf. and fur:not described

Form release / dosage:

Solution for infusion.

For 200 or 400 ml in glass bottles for blood, transfusion and infusion preparations with a capacity of 250 or 450 ml, respectively.

1 bottle with instruction for use is placed in an individual pack of cardboard. 15 bottles of 450 ml shta 28 bottles with 250 ml of 5 or 10 instructions for use, respectively, in corrugated cardboard boxes (for hospitals).

Packaging:bottles for blood and blood substitutes (1) -tacks, cardboard
bottles for blood and blood substitutes (15) - cardboard boxes
bottles for blood and blood substitutes (28) - cardboard boxes

Storage conditions:

Store in a dark place at a temperature of no higher than 25 ° C.

Keep out of the reach of children.

A short-term freezing of the drug during transportation is allowed.

Shelf life:

2 years. Do not use after the expiration date printed on the package.

Terms of leave from pharmacies:On prescription

Registration number:LSR-006066/08

Date of registration:31.07.2008

The owner of the registration certificate:ESKOM NPK, OAO ESKOM NPK, OAO Russia

Manufacturer: & nbsp

ESKOM NPK, OAO Russia

Information update date: & nbsp06.05.2011

Illustrated instructions

Instructions

Ringer's solution (Ringer solution)