Combined drug. Has analgesic, antipyretic, vasoconstrictive effect.
Paracetamol
Has antipyretic, analgesic and anti-inflammatory effect. Inhibits cyclooxygenase, mainly in the central nervous system, affects the centers of pain and thermoregulation. It does not have a negative effect on water-salt metabolism and mucous membranes of the gastrointestinal tract, and therefore has little effect on the synthesis of prostaglandins in peripheral tissues.
Phenylephrine
α1-adrenomimetic causes narrowing of arterioles and reduces the permeability of vessels of the nasal mucosa, reduces edema, facilitates breathing, reduces rhinorrhea and lacrimation. Causes dilated pupil without affecting accommodation, lowers intraocular pressure in glaucoma.
Ascorbic acid
Regulates the transport of hydrogen ions in oxidation-reduction reactions, including in the process at any stage of the Krebs cycle. Participates in the regulation of carbohydrate metabolism.Provides absorption of iron in the intestine, transferring it from trivalent into a divalent form, facilitating its incorporation into heme. Participates in the formation of tetrahydrofolic acid, the synthesis of steroid hormones, norepinephrine and adrenaline, collagen, prothrombin, glycogen. Inactivates hyaluronidase, activating the regeneration of tissues and normalizing the permeability of capillaries. Disinfects toxins and has an antioxidant effect, catching free radicals. He takes an active part in the regulation of immune processes: enhances the formation of antibodies, phagocytic activity and the synthesis of interferon. It inhibits the release of histamine and strengthens its degeneration, suppresses the release of mediators of inflammation and allergic reactions.
Lengthens the action of paracetamol by slowing its excretion and improves its tolerability.