Respiratory tract infections and ENT organs: otitis media (acute otitis media in children - 100 mg / kg per day, 250 mg / m2 body surface per day, 4 times a day - the effect of antibacterial therapy is moderate; ORZ of the upper respiratory tract, acute rhinitis with purulent discharge: children up to 2 years - 125 mg 4 times a day, the effect of antibacterial therapy is moderate, the use is not recommended), bronchitis (exacerbation of chronic obstructive bronchitis: adults inside the capsule for 0.5-1 g every 6 hours, 3-4 days), pneumonia (in children, in children under 5 years - intramuscularly 100 mg / kg per day 4 times a day), sinusitis (250 mg 4 times a day, 7 days), tonsillitis, pharyngitis , lung abscess.
Infections of the kidneys and the urinary tract (in pregnant - in / 2 grams every 4 hours in combination with gentamicin; 500 mg orally two times a day, 5 days - many modes of application of antibiotics effective to select a suitable mode insufficient data; 500 mg every 4 times a day), pyelonephritis (w / 1g every 6 hours - 3 days, followed by 500 mg oral 4 times a day in combination with gentamicin), pyelitis, cystitis (500 mg four times a day, 10 days), urethritis - 0.5 g 4 times a day.
Gonorrhea (500 mg 4 times a day, 5 days in combination with probenecid, once 3.5 g in combination with probenecid) - inside 3.5 g once or in / m 0.5 g 2 times for one day; with gonorrheal uncomplicated urethritis - once 0.5 g.
Infections of the musculoskeletal system (purulent arthritis in children, gonococcal arthritis: orally 3.5 g / day in combination with probenecid, then 2 g / day for 7 days).
Infections of the gastrointestinal tract: salmonellosis (with easy flow does not affect the outcome of treatment), children - 100 mg / kg per day, 5 days, salmonella, typhoid (1 g every 6 hours, 10 days, children - first in / in , then orally 100 mg / kg per day, 7 days) and paratyphoid, shigellosis (500 mg 4 times a day, 5 days).
Infections of the biliary system: cholangitis (iv 500 mg 4 times a day in combination with metronidazole and ceftazidime, iv or 4 g / day in combination with gentamycin), cholecystitis (500 mg 4 times a day, 5 days; see "Cholangitis").
Peritonitis (intravenously 2 g 2 times a day in combination with nonimmitsicin, metronidazole).
Infections of the skin and soft tissues (oral 500 mg 4 times a day, 5-10 days): erysipelas, impetigo (newborns - inside 50 mg 4 times a day), secondarily infected dermatoses (more often caused by golden staphylococci, only 13% are sensitive to ampicillin).
Infection endocarditis: prophylaxis (in cardiac surgery - 1 g during surgery and then every 6 hours for 48 hours in combination with cloxacillin, in combination with aminoglycosides) and treatment.
Meningitis - acute bacterial meningitis in children with the inability to use cephalosporins of the third generation (ceftriaxone, cefotaxime), variants: iv in 160-400 mg / kg per day 4 times a day in combination with chloramphenicol (iv 25-100 mg / kg every 6 hours), in some cases after 5 days - switching to oral therapy; in / in combination with chloramphenicol (first dose of chloramphenicol 50 mg / kg, then 25 mg / kg every 6 hours), a loading dose of ampicillin is 75 mg / kg, then 50 mg / kg every 4 hours for 10 days , with meningococcal meningitis - 7 days) - 14 g / day, multiplicity of 6-8 times a day.
Bacterial septicemia, sepsis (intramuscularly, intravenously in combination with aminoglycosides, 0.5-3 g 4 times a day, 7-11 days, this scheme is inferior in clinical efficacy and safety of monotherapy with modern beta-lactam drugs of a wide spectrum of action).
Listeriosis (first-line drug - IV in high doses, course not less than 2 weeks) - in / m or IV at 50 mg / kg every 6 hours. Inside adults - 0.25 g 4 times a day for 0, 5-1 h before meals with a little water; if necessary 3 g / day. Intramuscularly and intravenously, adults with infections of moderate severity 0.25-0.5 g every 6-8 hours; with severe infections 1-2 g 3-4 times a day.Course 5-10 days for 2-3 weeks, with chronic processes - a few months.