Included in the formulation
АТХ:R.05.C.A Expectorants
Pharmacodynamics:It is a plant of plant origin. The extract of ivy leaves contains saponins, triterpenoids, hederosaponins, alpha-hederin, flavonoids (kempferol derivatives, rutin). Reduces the viscosity of sputum and promotes its spillage. The drug improves microcirculation, raises diuresis, manifests nephro- and hepatoprotective properties, promotes the excretion of uric acid salts.
Activation of ß2-receptors in bronchial muscle cells and lung epithelium stimulates adrenergic effects. This leads to a decrease in the composition of intracellular Ca2+ in the muscles of the bronchi and relaxation of the bronchi. Simultaneously with this process, as a result of stimulation of ß2-activity, epithelial alveolar cells of the lungs of type II producemore surfactant.
The drug does not lead to a deterioration in the central regulation of respiration.
Pharmacokinetics:Not described.
Indications:Infectious and inflammatory diseases of the upper respiratory tract and bronchial tubes with hard-to-recover sputum (acute and exacerbation of chronic): bronchitis, tracheobronchitis, bronchial asthma, bronchiectatic disease, bronchospasm, difficulty in separating sputum and / or increasing its viscosity, cough (including dry).
X.J40-J47.J42 Chronic bronchitis, unspecified
X.J20-J22.J20 Acute bronchitis
X.J30-J39.J37 Chronic laryngitis and laryngotracheitis
X.J00-J06.J04 Acute laryngitis and tracheitis
Contraindications:Hypersensitivity, arginine succinate synthase deficiency, thyroid dysfunction, severe cardiovascular disease, pregnancy, lactation.
For syrup - fructose intolerance. For drops - increased sensitivity to mint oil, bronchial asthma, predisposition to laryngospasm, children under 2 years (the possibility of laryngospasm).
Carefully:Patients with diabetes should take into account that 5 ml of syrup contain 1.75 g of sorbitol (0.15 XE).
Pregnancy and lactation:The use of the drug is contraindicated in pregnancy and during breastfeeding, as there are no safety data on the use of the drug in these periods.
Dosing and Administration:The extract of ivy leaves is taken orally, used in the form of inhalations. Dosage, mode of administration, duration of treatment depends on the indications and age of the patient.
Inside adults and children older than 10 years - 5 ml or 25-30 drops (1 ml = 30 drops) 3-4 times a day, which corresponds to 300-400 mg of the active substance. With acute symptoms, a single dose can be increased, or the multiplicity of the appointment increased. The minimum duration of treatment is 1 week; it is recommended to continue therapy for another 2-3 days after the disappearance of the symptoms of the disease. Children 4-10 years - 2.5 ml 4 times a day, children 1-4 years - 2.5 ml 3 times a day, children under 1 year - 2.5 ml 2 times a day.
If there is no improvement, you need to see a doctor.
Side effects:Allergic reactions, nausea, rarely - pain in the epigastric region.
Overdose:When an overdose develops headache, nausea, diarrhea, vomiting, gastroenteritis, blood pressure may rise.It is necessary to cancel the drug, carry out symptomatic treatment.
Interaction:Simultaneous reception with antitussive drugs makes it difficult to divorce diluted sputum.
Special instructions:It is permissible to cloud and change the taste of the solution due to the content of extracts in the preparation.