Individual, determined by the patient's condition, the value of blood pressure, heart rate, hematocrit.
Intravenously sprayed, drip-drip and drip. Doses and the speed of administration of the drug should be selected individually, in accordance with the indications and condition of the patient.
Immediately before the use of the drug, with the exception of urgent cases, cutaneous test. To do this, after treatment with ethanol at the injection site in the middle of the inner surface of the forearm, 0.05 ml is injected intradermally to form a lemon crust. The presence of redness in the injection site with a diameter of more than 1.5 mm,pools or the appearance of symptoms of the general reaction of the organism in the form of nausea, dizziness and other manifestations 10-15 min after injection, indicates a hypersensitivity of the patient to the drug (risk group).
When using rheopolyglucin, bioassays: after slow administration of the first 5 drops of the drug, the transfusion is stopped for 3 minutes, then another 30 drops are introduced and the infusion is again stopped for 3 minutes. In the absence of a reaction, the administration of the drug continues. The results of the bioassay are necessarily recorded in the medical history.
1. When there is a violation of capillary blood flow (various forms of shock) injected / drip or jet-drip, in a dose of 500 to 1500 ml, to stabilize the hemodynamic parameters in a life-sustaining level. If necessary, the amount of the drug can be increased to 2000 ml.
Children with various forms of shock are administered at the rate of 5-10 ml / kg, the dose can be increased if necessary to 15 ml / kg. It is not recommended to reduce the hematocrit value below 25%.
2. With cardiovascular and plastic operations injected / drip immediately before surgery, for 30-60 minutes in adults and children in doses of 10 ml / kg during operation adults - 500 ml for children - 15 ml / kg. After surgery, the drug is administered / drip (for 60 minutes) for 5-6 days at: adults - 10 ml / kg, single dose, for children up to 2-3 years - 10 ml / kg once a day for children to 8 years-7-10 ml / kg 1-2 times a day, children under 13 years-5-7 ml / kg 1-2 times a day. For children older than 14 years, the doses are the same as for adults.
3. In operations with artificial circulation the drug is added to the blood at a rate of 10-20 ml / kg of the patient to fill the oxygenator pump. The concentration of reopolyglucin in the perfusion solution should not exceed 3%. In the postoperative period, the doses of the drug are the same as for a violation of capillary blood flow.
4. With the aim of detoxification injected / drip in a single dose of 500 to 1250 ml (in children 5-10 ml / kg) for 60-90 minutes. If necessary, you can pour another 500 ml of the drug in the first day (in children the administration of the drug in the first day can be repeated in the same doses). In the following days, the drug is administered drip, adults in a daily dose of 500 ml, children - at a rate of 5-10 ml / kg. Together, it is advisable to introduce crystalloid solutions (Ringer and Ringer-acetate, etc.), in such an amount as to normalize the water-electrolyte balance (especially important in the treatment of dehydrated patients and after surgical operations), reopolyglucinum, as a rule, causes an increase in diuresis indicates dehydration of the patient's body).
5. In ophthalmic practice is applied by electrophoresis, which is carried out in a conventional manner.The drug consumption per procedure is 10 ml. The procedure is carried out once a day, injected from both the positive and negative pole. The current density is up to 1.5 mA / cm2. The duration of the procedure is 15-20 min. The course of treatment consists of 5-10 procedures.