Fat-soluble vitamins can accumulate in tissues. In overdose, they are more toxic than water-soluble.
Symptoms acute overdose of vitamin A (develop 6 hours after taking in a dose of 300,000 units to 1 million units (120-400 pills) once): drowsiness, lethargy, diplopia, dizziness, severe headache, nausea, severe vomiting, diarrhea, irritability , osteoporosis, bleeding from the gums, dryness and ulceration of the oral mucosa, exfoliation of the lips, skin (especially the palms), agitation, confusion. The clinic is reversible.
Treatment: drug cancellation; symptomatic therapy.