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  • Dosage form: & nbspfilm-coated tablets
    Composition:

    1 tablet, film-coated, contains:

    active substances: thiamine hydrochloride 100.00 mg, pyridoxine hydrochloride 200.00 mg, cyanocobalamin 0.20 mg;

    Excipients: microcrystalline cellulose 80.0 mg, magnesium stearate 4.8 mg, povidone 15.0 mg;

    sheath: macrogol 6000 9.0 mg, titanium dioxide 11.25 mg, talc 30.0 mg, hypromellose 7.5 mg, methyl methacrylate and ethyl acrylate copolymer 1: 2 [dispersion 30%] 2.25 mg.

    Description:

    Round, biconvex tablets, white or almost white, covered with a film membrane. On a cross-section from white to light pink color with impregnations from light pink to dark pink color.

    Pharmacotherapeutic group:Multivitamins
    ATX: & nbsp

    A.11.B.A   Multivitamins

    Pharmacodynamics:

    Pharmacological action is determined by the properties of the vitamins that make up the drug.

    Thiamine (vitamin B1) in the human body, as a result of phosphorylation processes, it turns into cocarboxylase, which is the coenzyme of many enzyme reactions. Thiamine plays an important role in the carbohydrate, protein and fat metabolism. Actively participates in the processes of carrying out nervous excitation in the synapses.

    Pyridoxine (vitamin B6) necessary for normal operation central and peripheral nervous system. In the phosphorylated form is a coenzyme in the metabolism of amino acids (decarboxylation, reamination, etc.). Acts as a coenzyme of the most important enzymes that act in the nerve tissues. Participates in the biosynthesis of many neurotransmitters - such as dopamine, norepinephrine, epinephrine, histamine and gamma-aminobutyric acid.

    Cyanocobalamin (vitamin B12) is necessary for normal hematopoiesis and ripening of erythrocytes, and also participates in a number of biochemical reactions that ensure the vital activity of the organism - in the transfer of methyl groups, in the synthesis of nucleic acids, protein, in the exchange of amino acids, carbohydrates, lipids. Has a beneficial effect on the processes in the nervous system (the synthesis of nucleic acids and the lipid composition of cerebrosides and phospholipids). Coenzyme forms of cyanocobalamin - methylcobalamin and adenosylcobalamin are necessary for replication and cell growth.

    Indications:

    It is used in the complex therapy of the following neurological diseases:

    - polyneuropathy of various etiologies (diabetic, alcoholic, etc.);

    - intercostal neuralgia;

    - trigeminal neuralgia;

    - radicular syndrome caused by degenerative changes in the spine;

    cervical syndrome;

    - Shoulder-scapular syndrome;

    - lumbar syndrome;

    - Lumboeishalgia.

    Contraindications:

    Hypersensitivity to the components of the drug.

    Children's age (effectiveness and safety of the drug are not investigated).

    Pregnancy and lactation:

    Due to the limited experience with Neuromultivitis®, it is not recommended to prescribe it during pregnancy and breastfeeding.

    Dosing and Administration:

    Tablets should be taken after meals, without chewing and washing down with a small amount of liquid.

    Assign 1 tablet 1-3 times a day.

    The duration of the course is according to the doctor's recommendation.

    Do not recommend treatment with high doses of the drug for more than 4 weeks.

    Side effects:

    Neuromultiv® well tolerated by patients. In isolated cases, nausea, tachycardia, skin reactions in the form of pruritus and urticaria may occur.

    Overdose:

    Clinical symptoms overdoses of vitamins contained in Neuromultiv® can be expected only after taking exceptionally high doses for a very long time.

    Vitamin B1 - no symptoms of an overdose after oral administration.

    Vitamin B6 - after taking more than 2 grams per day, neuropathies with ataxia and sensitivity disorders, convulsions with EEG changes and, in some cases, hypochromic anemia and seborrheic dermatitis are described.

    Vitamin B12 - after parenteral administration (in rare cases and after ingestion), eczematous skin and acne changes were observed.

    Treatment symptomatic.

    Interaction:

    Pyridoxine reduces the antiparkinsonian efficacy of levodopa.

    Ethanol dramatically reduces the absorption of thiamine.

    During the administration of Neuromultivitis®, the use of multivitamin complexes, which include vitamins of group B, is not recommended.

    Special instructions:

    Cyanocobalamin can mask the symptoms of folic acid deficiency.

    Effect on the ability to drive transp. cf. and fur:

    Neuromiltiv® does not affect the ability to drive vehicles and mechanisms.

    Form release / dosage:

    Film-coated tablets.

    Packaging:

    For 20 tablets in PVC / Al blister.

    For 1 or 3 blisters together with instructions for use in a cardboard box.

    Storage conditions:

    In dry, the dark place at a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    3 years.

    Do not use after the expiration date.

    Terms of leave from pharmacies:On prescription
    Registration number:П N013734 / 01
    Date of registration:26.12.2011 / 15.05.2017
    Expiration Date:Unlimited
    The owner of the registration certificate:VALEANT, LLC VALEANT, LLC Russia
    Manufacturer: & nbsp
    Representation: & nbspVALEANT LLC VALEANT LLC Russia
    Information update date: & nbsp27.06.2018
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