Allergic reactions: urticaria, chills or fever, rash, skin itch, rarely - bronchospasm, eosinophilia, malignant exudative erythema (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome), angioedema, rarely anaphylactic shock.
From the central nervous system: headache, dizziness.
From the gastrointestinal tract: nausea, vomiting, diarrhea or constipation, flatulence, abdominal pain, dysbiosis, violation liver function, rarely - stomatitis, glossitis, pseudomembranous enterocolitis.
From the urinary system:
disturbance of kidney function, oliguria, interstitial nephritis.
From the hematopoiesis:
hemolytic anemia, leukopenia, neutropenia, granulocytopenia, thrombocytopenia,
hypocoagulation.
Laboratory indicators:
azotemia, increased urea concentration in the blood, increased activity of "liver" transaminases and alkaline phosphatase, hypercreatininemia, hyperbilirubinemia, Coombs positive reaction.
Local reactions:
morbidity and infiltration at the site of intramuscular injection.
Other: Superinfection (in particular, candidal vaginitis).