Andipal (Andipal)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceBendazole + Metamizol sodium + Papaverine + PhenobarbitalBendazole + Metamizol sodium + Papaverine + Phenobarbital
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  • Andipal
    pills inwards 
    UZOLE-SIBERIAN CHEMICAL PLANT, OJSC     Russia
  • Andipal
    pills inwards 
    DALHIMFARM, OJSC     Russia
  • Andipal
    pills inwards 
    PHARMSTANDART-TOMSKHIMFARM, OJSC     Russia
  • Andipal
    pills inwards 
    Barnaul Plant of Medical Preparations, LLC     Russia
  • Andipal
    pills inwards 
    IRBITSK HFZ, OJSC     Russia
  • Andipal
    pills inwards 
    MOSCOW ENDOCRINE FACTORY, FSUE     Russia
  • Andipal
    pills inwards 
    URALBIOFARM, OJSC     Russia
  • Andipal
    pills inwards 
    UZOLE-SIBERIAN CHEMICAL PLANT, OJSC     Russia
  • Andipal Avexima
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    ASFARMA, LLC     Russia
    • Dosage form: & nbsppills
    Composition:

    Active substances: metamizole sodium - 250 mg, phenobarbital - 20 mg, dibazol - 20 mg, papaverine hydrochloride - 20 mg;

    Excipients: potato starch, talc, stearic acid.
    Description:

    Tablets white or white with a weak yellow shade of color, flat-cylindrical with a facet and a risk.

    Pharmacotherapeutic group:Analgesic agent (analgesic non-narcotic agent + antispasmodic agent + barbiturate)
    ATX: & nbsp

    N.02.B.B.52   Metamizole sodium in combination with other drugs, excluding psycholeptics

    Pharmacodynamics:

    Combined drug. The combination of the components of the drug leads to a mutual enhancement of their pharmacological action.

    Metamizole sodium - a derivative of pyrazolone, has an analgesic and antipyretic effect.

    Bendazol (dibasol) - a vasodilating agent; has a vasodilating action, stimulates the function of the spinal cord. Has direct spasmolytic effect on smooth muscles of blood vessels and internal organs. It facilitates synaptic transmission in the spinal cord.

    Papaverina hydrochloride is an antispasmodic, has hypotensive effect, reduces tone and relaxes smooth muscles of internal organs and vessels. Phenobarbital, in small doses has a sedative effect and enhances the effect of other components.

    Indications:

    Pain syndrome (mild or moderate) with spasms of smooth muscles of internal organs: renal colic, biliary colic, intestinal colic; biliary dyskinesia, postcholecystectomy syndrome; spasm of ureters and bladder; algodismenorea.

    Spasm of cerebral vessels, migraine.

    As an auxiliary medicine: pain syndrome after surgical interventions and diagnostic procedures.

    Contraindications:

    Hypersensitivity (including the derivatives of pyrazolone); oppression of bone marrow hematopoiesis; marked hepatic and / or renal insufficiency; deficiency of glucose-6-phosphate dehydrogenase; tachyarrhythmias, severe angina pectoris, collapse, decompensated chronic heart failure; angle-closure glaucoma; hyperplasia of the prostate; intestinal obstruction, megacolon; pregnancy, lactation.

    Dosing and Administration:

    Inside, 1 tablet 2-3 times a day.

    The duration of the application without consulting a doctor should not exceed 7 days.

    Side effects:

    Allergic reactions.

    From the central nervous system: drowsiness, decreased speed of psychomotor reactions.

    From the gastrointestinal tract: nausea, constipation.

    From the cardiovascular system: arterial hypotension.

    With prolonged use: leukopenia, agranulocytosis, impaired liver and kidney function.

    Interaction:

    Combination with nitrates (nitroglycerine, nitrosorbide, joint, etc.), calcium channel blockers (nifedipine, Corinfar, etc.), beta-blockers (anaprilin, metoprolol, talinolol and others), ganglion blockers (pentamine, etc.), diuretics (furosemide, hypogiazide, etc.), myotropic antispasmodics (dipyridamole, eufillin, etc.) enhances the hypotensive effect of these drugs.

    Simultaneous use with other non-narcotic analgesics can lead to mutual enhancement of toxic effects.

    Joint application with adsorbents, astringents and enveloping agents reduces the absorption of the drug in the gastrointestinal tract.

    Special instructions:

    At long (more than 7 days) application control of a picture of peripheric blood and a functional status of a liver is necessary.

    If there is no effect within 3 days, stop taking the drug and consult a doctor.

    Effect on the ability to drive transp. cf. and fur:During treatment should be abandoned the employment of potentially hazardous activities that require increased concentration and speed of psychomotor reactions.
    Form release / dosage:

    Pills.

    Packaging:For 10 tablets in a contiguous cell-free or contiguous cell package. Contour-free cell or cell packs, together with an equal number of instructions for use, are placed in a group package.
    Storage conditions:

    In a dry place, protected from light and inaccessible to children.

    Shelf life:

    2 years 6 months Do not use after the time specified on the package.

    Terms of leave from pharmacies:Without recipe
    Registration number:LS-000733
    Date of registration:06.08.2010
    Expiration Date:Unlimited
    The owner of the registration certificate:DALHIMFARM, OJSC DALHIMFARM, OJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp05.09.2017
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