Andipal (Andipal)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceBendazole + Metamizol sodium + Papaverine + PhenobarbitalBendazole + Metamizol sodium + Papaverine + Phenobarbital
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  • Andipal
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    UZOLE-SIBERIAN CHEMICAL PLANT, OJSC     Russia
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    DALHIMFARM, OJSC     Russia
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    PHARMSTANDART-TOMSKHIMFARM, OJSC     Russia
  • Andipal
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    Barnaul Plant of Medical Preparations, LLC     Russia
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    IRBITSK HFZ, OJSC     Russia
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    MOSCOW ENDOCRINE FACTORY, FSUE     Russia
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    UZOLE-SIBERIAN CHEMICAL PLANT, OJSC     Russia
  • Andipal Avexima
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    ASFARMA, LLC     Russia
    • Dosage form: & nbsppills
    Composition:

    Active substances: metamizole sodium (analgin) - 0.25 g, phenobarbital - 0.02 g, bendazole (dibazol) - 0.02 g, papaverine hydrochloride - 0.02 g.

    Excipients: potato starch - 0.04779 g, talc, - 0.00925 g, stearic acid - 0.00296 g.

    Description:
    Round tablets white or white with a yellowish tint of color, flat-cylindrical, with a facet and a risk.
    Pharmacotherapeutic group:Analgesic agent (analgesic non-narcotic agent + antispasmodic agent + barbiturate)
    ATX: & nbsp

    N.02.B.B.52   Metamizole sodium in combination with other drugs, excluding psycholeptics

    Pharmacodynamics:

    Combined drug. The combination of the components of the drug leads to a mutual enhancement of their pharmacological action.

    Metamizole sodium - a derivative of pyrazolone, has an analgesic and antipyretic effect.

    Bendazol (dibasol) - a vasodilating agent; has a vasodilating action, stimulates the function of the spinal cord. Has direct spasmolytic effect on smooth muscles of blood vessels and internal organs. It facilitates synaptic transmission in the spinal cord.

    Papaverina hydrochloride is an antispasmodic, has hypotensive effect, reduces tone and relaxes smooth muscles of internal organs and vessels. Phenobarbital, in small doses has a sedative effect and enhances the effect of other components.

    Indications:

    Pain syndrome (mild or moderate) with spasms of smooth muscles of internal organs: renal colic, biliary colic, intestinal colic; biliary dyskinesia, postcholecystectomy syndrome; spasm of ureters and bladder; algodismenorea.

    Spasm of cerebral vessels, migraine.

    As an auxiliary medicine: pain syndrome after surgical interventions and diagnostic procedures.

    Contraindications:

    Hypersensitivity (including the derivatives of pyrazolone); oppression of bone marrow hematopoiesis; marked hepatic and / or renal insufficiency; deficiency of glucose-6-phosphate dehydrogenase; Children under the age of 8, pregnancy, lactation period, tachyarrhythmias, severe angina, collapse, decompensated chronic heart failure; angle-closure glaucoma; hyperplasia of the prostate; intestinal obstruction, megacolon.

    Carefully:
    Arterial hypotension, peripheral blood disease, liver failure.
    Dosing and Administration:

    Inside, adults and children older than 8 years, 1 tablet 2-3 times a day.

    The duration of the application without consulting a doctor should not exceed 7 days.

    Side effects:

    Allergic reactions.

    From the central nervous system: drowsiness, decreased speed psychomotor reactions.

    From the gastrointestinal tract: nausea, constipation.

    From the cardiovascular system: arterial hypotension.

    With prolonged use: leukopenia, agranulocytosis, impaired liver and kidney function.

    Interaction:

    Combination with nitrates (nitroglycerine, nitrosorbide, joint, etc.), calcium channel blockers (nifedipine, Corinfar, etc.), beta-blockers (anaprilin, metoprolol, talinolol and others), ganglion blockers (pentamine, etc.), diuretics (furosemide, hypothiazide, etc.), myotropic antispasmodics (dipyridamole, eufillin, etc.) enhances the hypotensive effect of these drugs.

    Simultaneous use with other non-narcotic analgesics can lead to mutual enhancement of toxic effects.

    Joint application with adsorbents, astringents and enveloping agents reduces the absorption of the drug in the gastrointestinal tract.

    Special instructions:

    At long (more than 7 days) application control of a picture of peripheric blood and a functional status of a liver is necessary.

    If there is no effect within 3 days, stop taking the drug and consult a doctor.

    For children and adolescents under 18, the drug should be used only as directed by the doctor.

    Effect on the ability to drive transp. cf. and fur:
    During treatment should be abandoned the employment of potentially hazardous activities that require increased concentration and speed of psychomotor reactions.
    Form release / dosage:
    Tablets 20 mg + 250 mg + 20 mg + 20 mg.
    Packaging:

    For 10 tablets in a contour cell or non-jammed packaging without attachment to a pack of cardboard.

    For 500 contour mesh or cellless packages together with an equal number of instructions for use in a cardboard box for consumer packaging (for inpatient).

    Storage conditions:

    In a dry, the dark place at a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    2 years and 6 months. The drug should not be used after the expiration date.

    Terms of leave from pharmacies:Without recipe
    Registration number:LS-002641
    Date of registration:26.03.2012 / 15.10.2013
    Expiration Date:Unlimited
    The owner of the registration certificate:Barnaul Plant of Medical Preparations, LLC Barnaul Plant of Medical Preparations, LLC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp15.08.2017
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