Elufoor - instructions for use, doses, side effects, contraindications

Hard gelatin capsules number 0. The body and the lid of yellow color are opaque. The contents of the capsules are a mixture of powder and granules of yellow color. It is possible to compact the contents of the capsules into lumps that crumble when pressed.

Pharmacotherapeutic group:Antimicrobial agent - nitrofuran

ATX: & nbsp

A.07.A.X.03 Nifuroxazide

Pharmacodynamics:

Nifuroxazide is a derivative of nitrofuran, it has an antimicrobial effect.

Highly active in relation to Campylobacter jejuni, Escherichia coli, Salmonella spp., Shigella spp; Clostridium perfringens, Vibrio cholerae, pathogenic Vibrions and Vibrio parahaemolyticus, Staphylococcus spp.

Weakly sensitive to nifuroxazide: Citrobacter spp, Enterobacter cloacae, Proteus indologenes.

Resistant to nifuroxazide: Klebsiella spp, Proteus mirabilis, Providencia spp., Pseudomonas spp.

Presumably blocks the activity of dehydrogenases and depresses respiratory chains, a cycle of tricarboxylic acids and a number of other biochemical processes in the microbial cell. Does not disturb the balance of the intestinal microflora. With acute bacterial diarrhea, eubiosis of the intestine is restored.When infected with enterotroptic viruses prevents the development of bacterial superinfection.

Pharmacokinetics:

After oral administration nifuroxazide practically not absorbed from the gastrointestinal tract and does not have a systemic effect; 99% of the dose taken remains in the intestine and renders its antimicrobial effect there. Nifuroxazide is excreted by the intestine: 20% unchanged, and the rest of the nifuroxazide is chemically altered.

Indications:

Acute bacterial diarrhea, proceeding without deterioration of the general condition, fever, intoxication.

Contraindications:

- Hypersensitivity to nifuroxazide, nitrofuran derivatives or any excipients of the drug;

- Children under 3 years old (for this dosage form);

- pregnancy;

- deficiency of sugar / isomaltase, intolerance to fructose, glucose-galactose malabsorption.

Pregnancy and lactation:

In studies on animals, there was no teratogenic effect. However, as a precautionary measure, nifuroxazide during pregnancy is not recommended.

During the lactation period, it is possible to continue breastfeeding in the case of a short course of treatment with the drug. It is necessary to consult a doctor.

Dosing and Administration:

Inside. Capsule should be swallowed whole, washed down with a small amount of water. Adults: 1 capsule of 200 mg 4 times a day (the interval between meals is 6 hours).

Children from 6 to 18 years: 1 capsule of 200 mg 3-4 times a day (the interval between doses of 6-8 h).

Children from 3 to 6 years: 1 capsule of 200 mg 3 times a day (the interval between meals is 8 hours).

The duration of the course of treatment is 5-7 days, but not more than 7 days.

If there is no improvement within the first 3 days, you should consult a doctor.

Use the drug only according to the method of administration and the doses specified in the instructions. If necessary, please consult with your doctor before using the medication.

Side effects:

Allergic reactions (skin rash, hives, Quincke's edema, anaphylactic shock).

If any of the side effects listed in the manual are aggravated, or if you notice any other side effects not listed in the instructions, tell your doctor.

Overdose:

Symptoms of overdose are not known.

Treatment is symptomatic.

Interaction:

It is not recommended simultaneous use with drugs causing development of disulfiram-like reactions, drugs depressing the central nervous system.

If you are taking other medications (including over-the-counter drugs) before using Elufor, consult your doctor.

Special instructions:

When treating diarrhea concomitantly with nifuroxazide therapy, rehydration therapy should be performed.

In the case of bacterial diarrhea with signs of systemic damage (worsening of the general condition, fever, symptoms of intoxication or infection), you should consult a doctor about deciding whether to use antimicrobial agents of systemic action.

The daily dose of 800 mg contains 0.023 XE.

During the treatment with the drug Elufror, alcohol is prohibited.

If symptoms of an allergic reaction appear (including shortness of breath, rash, itching), stop taking the medication and consult a doctor.

Effect on the ability to drive transp. cf. and fur:

The drug does not affect the ability to drive vehicles and mechanisms.

Form release / dosage:Capsules, 200 mg.

Packaging:

For 5, 6 or 10 capsules in a contour mesh box made of polyvinylchloride film and aluminum foil printed lacquered.

10, 20, 30, 40, 50 or 100 capsules in cans of polyethylene terephthalate for medicinal products sealed with caps screwed on with first opening control or with a "push-turn" system of polypropylene or polyethylene or polypropylene cans for drugs sealed with lids pulled from control of the first opening from polyethylene or cans of polypropylene for medicines sealed with lids pulled with the control of the first opening of high pressure polyethylene.

One jar or 1, 2, 3, 4, 5, 6 or 10 contour squares, together with the instructions for use, are placed in a cardboard package (bundle).

Storage conditions:

At a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

3 years.

Do not use the drug after the expiration date.

Terms of leave from pharmacies:Without recipe

Registration number:LP-004015

Date of registration:08.12.2016

Expiration Date:08.12.2021

The owner of the registration certificate:ATOLL, LLC ATOLL, LLC Russia

Manufacturer: & nbsp

OZONE, LLC Russia

Representation: & nbspOZONE LLC OZONE LLC Russia

Information update date: & nbsp19.01.2017

Illustrated instructions

Instructions

Elufor (Elufor)