Stoppier - instructions for use, dose, side effects, contraindications

Nifuroxazide is highly active against Campylobacter jejuni, Escherichia coli, Salmonella spp., Shigella spp.; Clostrifium perfringens, Vibrio cholerae, pathogenic Vibrions and Vibrio parahemolytique, Staphylococcus spp. Weakly sensitive to nifuroxazide: Citrobacter spp., Enterobacter cloacae and Proteus indologenes. Resistant to nifuroxazide: Klebsiella spp., Proteus mirabilis, Providencia spp., Pseudomonas spp.

Nifuroxazide does not affect the composition of the normal bacterial flora of the digestive tract.

Nifuroxazide presumably inhibits the activity of dehydrogenases and the synthesis of proteins in bacterial cells. Does not cause the emergence of drug-resistant strains, nor was there a cross-resistance with other antibacterial drugs, which allows, if necessary, in generalized infections to use it in complex therapy with systemic drugs.When intestinal infections of viral origin prevents the development of bacterial superinfection. The effectiveness of nifuroxazide does not depend on pH in the lumen of the intestine, nor on the sensitivity of microorganisms to antibacterial drugs. The drug is practically not absorbed from the digestive tract, it acts exclusively in the lumen of the intestine. The effect manifests itself from the first hours of treatment.

Pharmacokinetics:

Nifuroxazide is excreted by the intestine: 20% unchanged, and the rest of the nifuroxazide is chemically altered.

Indications:

Acute bacterial diarrhea, proceeding without deterioration of the general condition, fever, intoxication.

Contraindications:

Hypersensitivity to nifuroxazide, nitrofuran derivatives or any excipients of the drug.

Children under 3 years.

Pregnancy.

Intolerance to fructose, glucose-galactose malabsorption syndrome or insufficiency of sucrose and isomaltase (due to the presence of sucrose in the formulation).

Pregnancy and lactation:

Pregnancy

Use during pregnancy is contraindicated.

Breastfeeding period

Breastfeeding is permissible only in the case of a short course of treatment with the drug.

Dosing and Administration:

Inside. Adults and children over 6 years of age per 1 capsule (200 mg) 4 times a day; daily dose of 800 mg. Children 3-6 years for 1 capsule (200 mg) 3 times a day; daily dose of 600 mg. If there is no improvement within the first three days, you should consult a doctor.

Side effects:

Allergic reactions, such as skin rashes, hives, Quincke's edema, anaphylactic shock.

If any of the side effects listed in the manual are aggravated, or if you notice any other side effects not listed in the instructions, tell your doctor.

Overdose:

No data.

Interaction:

With the simultaneous use of ethanol, a disulfiram-like reaction may develop (abdominal pain, nausea, vomiting, headache, tachycardia, fuzzy vision, weakness, convulsions). It is not recommended simultaneous use with drugs that depress the central nervous system.

Special instructions:

- In the case of bacterial diarrhea with signs of systemic damage (worsening of the general condition, fever, symptoms of intoxication or infection), you should consult a doctor to decide on the use of antibacterial drugs of systemic action.

- The drug Stopdiar should be applied no more than 7 days. Indications for long-term therapy are absent. If persistent diarrhea persists for more than 3 days, consult a doctor.

- In the case of severe invasive diarrhea, it is recommended to use systemic antibiotics, since nifuroxazide It is not absorbed in the gastrointestinal tract.

- With the development of hypersensitivity reactions (dyspnea, swelling of the face, lips, tongue, skin rash, itching), Stoppior should be stopped immediately.

- Against the background of taking the drug Stopdiar, you must follow a diet, including the exclusion of juices, raw vegetables and fruits, spices and heavy meals.

- During the reception of Stopdiar in the treatment of acute diarrhea, permanent rehydration therapy (oral or intravenous) should be performed depending on the general condition of the patient.

- During the treatment with nifuroxazide, alcohol is prohibited.

Effect on the ability to drive transp. cf. and fur:

The drug does not affect the ability to drive vehicles and mechanisms.

Form release / dosage:

Capsules 200 mg.

Packaging:

For 12 capsules in a blister of PVC and aluminum foil.

One blister along with the instructions for use are placed in a cardboard box.

Storage conditions:

At a temperature of no higher than 25 ° C.

Keep out of the reach of children!

Shelf life:

2 years.

Do not use the product after the expiry date printed on the package.

Terms of leave from pharmacies:Without recipe

Registration number:LP-003395

Date of registration:29.12.2015

Expiration Date:29.12.2020

The owner of the registration certificate:GEDEON RICHTER, OJSC GEDEON RICHTER, OJSC Hungary

Manufacturer: & nbsp

GEDEON RICHTER, Plc. Hungary

Representation: & nbspGEDEON RICHTER OJSC GEDEON RICHTER OJSC Hungary

Information update date: & nbsp24.08.2016

Illustrated instructions

Instructions

Stoppier (Stopdiar)