Active substanceSimethiconeSimethicone
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  • Dosage form: & nbspemulsion
    Composition:

    In 1 ml (25 drops) of the preparation contains: Active substance: simethicone * - 40.00 mg Excipientsmacrogol stearate 6.560 mg, glyceryl monostearate 40-55-4.020 mg, carbomer 6,350 mg, banana flavor 4,233 mg, acesulfame potassium 0.318 mg, sorbitol liquid (noncrystallizing) 211.655 mg, sodium chloride 0.708 mg, sodium citrate - 4,445 mg, sodium hydroxide - 0,708 mg, sorbic acid - 1,060 mg, purified water - 778,245 mg.

    * Simethicone consists of dimethicone (polydimethylsiloxane (PDMS)) and silicon dioxide in a ratio of 96: 4

    Pharmacotherapeutic group:carminative
    ATX: & nbsp

    A.03.A.X   Other drugs used in bowel disorders

    Pharmacodynamics:

    Active substance - simethicone, reduces the amount of gases in the gastrointestinal tract (GIT): it has surface-active properties and the ability to reduce the surface tension at the liquid / gas interface, which makes it difficult to form gas bubbles, and also facilitates their fusion and destruction of the foam in the intestine, the released gas is absorbed or withdrawn by the natural by the influence of peristalsis of the intestine. The use of simethicone in preparation for conducting diagnostic studies prevents the occurrence of image defects caused by gas bubbles.


    Pharmacokinetics:

    Pharmacokinetics

    Simethicone is chemically inert, after ingestion it is not absorbed from the digestive tract and acts only in its lumen. Does not interact with microorganisms and enzymes and does not affect the digestive process. It is excreted intestine unchanged.

    Indications:
    • excessive formation and accumulation of gases in the digestive tract (flatulence, aerophagia, increased gas formation in the postoperative period, Remkheld's syndrome);

    • symptoms of excessive gassing caused by functional dyspepsia;

    • intestinal colic in newborns and infants;

    • preparation for diagnostic studies of the abdominal and pelvic organs (ultrasound, radiography, esophagogastroduodenoscopy, etc.), including, as an additive to suspensions of contrast agents for imaging by the method of double contrasting;

    • acute poisoning with detergents containing foaming agents (detergents), as a defoamer.

    Contraindications:Pincreased sensitivity to the components of the drug, intestinal obstruction, hereditary intolerance to fructose.
    Pregnancy and lactation:

    Preparation Espumizan® L can be used during pregnancy and during breastfeeding.

    Dosing and Administration:

    Inside. Before use, the vial of eMulcher must be shaken. Dosing the drug can be in droplets or in milliliters using a measuring cap. For drip dosing, the bottle must be held vertically with a hole down.

    The drug is taken during or after a meal and, if necessary, before going to bed. The frequency of administration and duration of use depend on the severity of the symptoms. If necessary, the drug Espumizan® L can be taken for a long time.

    With euAlalobs associated with excessive gassing and intestinal colic Children from birth to 1 year: 1 ml (25 drops) of the drug Espumizan® L at each feeding of the child (add in a bottle with a children's food or give by means of a small spoon during or after feeding).

    Children from 1 to 6 years: 1 ml (25 drops) of the drug Espumizan0 L 3-5 times a day. Children from 6 to 14 years: 1-2 ml each

    (25-50 drops) of the drug Espumizan® L 3-5 times a day.

    Children from 14 years and adults: 2 ml (50 drops) of the drug Espumizan® L 3-5 times a day.

    In preparation for radiography and ultrasound Apply 2 ml (50 drops) of the drug Espumizan® L 3 times a day the day before the study and 2 ml (50 drops) of the drug Espumizan® L in the morning on the day of the study.

    To obtain a double contrast image

    Add 4-8 ml of the drug Espumizan L per 1 liter of contrasting suspension.

    When preparing for esophagogastroduodenoscopy

    Inside for 4-8 ml of the drug Espumizan® L before the research. During the endoscopy, if necessary, it is possible to introduce several milliliters of emulsion through the endoscope channel to eliminate gas bubbles that interfere with the study.

    In case of acute poisoning with detergents containing detergents Children - 2.5-10 ml of the drug Espumizan® L, adults - 10-20 ml of the drug Espumizan® L depending on the severity of the poisoning.

    Side effects:PExterior effects with Espumizan® L were not observed. Possible development of allergic reactions to the auxiliary components of the drug.
    Overdose:not known
    Special instructions:

    In case of excess gas production and / or intestinal colic for a long time, you should consult a doctor for a medical examination.

    Preparation Espumizan ® L contains sorbitol (sorbitol), therefore its use in patients with hereditary intolerance to fructose is contraindicated. Information for patients with diabetes mellitus: in 1 ml of the solution (25 drops) contains 211.655 mg of sorbitol, which corresponds to 0.018 bread units (XE).


    Effect on the ability to drive transp. cf. and fur:

    Preparation Espumizan ® L does not affect the ability to drive vehicles and work requiring increased concentration of attention.

    Form release / dosage:

    Emulsion for oral administration, 40 mg / ml.

    To 30 ml in bottles of dark glass, equipped with a dropper dispenser, a screw cap with a system of monitoring the first opening and a measuring cap.

    1 bottle with instructions for use in a cardboard pack.

    Packaging:


    To 30 ml in bottles of dark glass, equipped with a dropper dispenser, a screw cap with a system of monitoring the first opening and a measuring cap.

    1 bottle with instructions for use in a cardboard pack.

    Storage conditions:

    Store at a temperature not exceeding 25 ° C. Keep out of the reach of children.

    Shelf life:

    3 years.

    Do not use after the expiration date of the drug.

    After opening the vial the drug should be used within 6 months.

    Terms of leave from pharmacies:Without recipe
    Registration number:П N013354 / 01
    Date of registration:07.09.2007
    The owner of the registration certificate:Berlin-Chemie, AGBerlin-Chemie, AG Germany
    Manufacturer: & nbsp
    Information update date: & nbsp05.08.2015
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