Hemodez-N - instructions for use, doses, side effects, contraindications

Povidone low molecular weight medical 8000 ± 2000	- 60 g
Sodium chloride	- 5.5 g
Potassium chloride	- 0.42 g
Calcium chloride hexahydrate	- 0.5 g
Magnesium chloride hexahydrate	0.005 g
Sodium bicarbonate	- 0.23 g
Water for Injection	up to 1 liter

Description:

Transparent liquid of light yellow or yellow color.

Pharmacotherapeutic group:Detoxifying agent

ATX: & nbsp

B.05.A.A Blood plasma preparations and plasma-substituting drugs

Pharmacodynamics:

The action of Hemodeza-H is due to the ability of low molecular weight polyvinylpyrrolidone to bind toxins circulating in the blood and quickly remove them from the body. Hemodez-H differs from Hemodesa by a lower molecular weight of polyvinylpyrrolidone. The decrease in the molecular weight of the polymer accelerates the excretion of it by the kidneys from the body and improves the detoxification properties of the preparation. It increases renal blood flow, increases glomerular filtration and increases diuresis.

Pharmacokinetics:

Metabolic transformations in the body are not exposed. Quickly excreted by the kidneys, within 4 hours 80% is output, and after 12 - 24 hours - completely.

Indications:

Shock (posttraumatic, postoperative, burn, hemorrhagic), intoxication (toxic diseases of the gastrointestinal tract: dysentery, dyspepsia, salmonellosis, as a means of detoxification in the postoperative period in peritonitis, liver disease,accompanied by the development of liver failure; intestinal obstruction; thyrotoxicosis; burn disease; acute radiation sickness; sepsis; pneumonia; acute phase of myocardial infarction; hemolytic disease of newborns; intrauterine infection and toxemia of newborns; Toxicosis of pregnant women.

Contraindications:

Hypersensitivity to the drug, intracranial hypertension, hemorrhagic stroke, condition after craniocerebral trauma, cardiovascular insufficiency IIb - III degree, respiratory failure, severe allergic reactions, thromboembolism, oliguria, anuria, acute nephritis, bronchial asthma, phlebothrombosis.

Carefully:Not described.

Pregnancy and lactation:Not described.

Dosing and Administration:

Intravenously drip (40 - 80 cap / min), through a device with a filter.

The dose depends on the age of the patient and the severity of intoxication.

Single dose for adults - 200-500 ml; for children - 5-10 ml / kg; the maximum single dose for infants is 50-70 ml, 2-5 years - 100 ml, 5-10 years -150 ml, 10-15 years - 200 ml. The drug is administered once or repeatedly (up to 2 times a day) for 1-10 days, depending on the severity of intoxication.In acute gastrointestinal infections, burn and radiation diseases are administered 1-2 times a day; with hemolytic disease and toxemia of newborns - 2-8 times a day (daily or every other day); with large focal myocardial infarction (in 1 day) - 200 ml once, with complications for 2 days - 200 ml.

Side effects:Not described.

Overdose:

In case of an overdose, the drug should be withdrawn and symptomatic therapy should be performed.

Special instructions:

With extensive burns combined with the introduction of plasma, albumin, gamma globulin.

Before starting the infusion, the doctor must check the integrity and integrity of the package. The drug should be clear, free of sediment, sediment and mold. The results of visual inspection are recorded in the medical history.

Before administration, the solution is warmed to body temperature.

Effect on the ability to drive transp. cf. and fur:Not described.

Form release / dosage:Solution for infusion.

Packaging:

100, 200, 250, 400 and 500 ml in glass bottles of MTO grade for blood, transfusion and infusion preparations with a capacity of 100, 250, 450 and 500 ml respectively.

One bottle with instructions for medical use of the drug is placed in a pack of boxboard.

For 28 bottles with a capacity of 100, 250 ml or 15 bottles with a capacity of 450, 500 ml with 5-10 instructions for medical use are placed in a box of gorirovanncardboard [for hospitals].

Storage conditions:At a temperature of no higher than 25 ° C. Keep out of the reach of children.

Shelf life:3 years.

Terms of leave from pharmacies:On prescription

Registration number:LS-002115

Date of registration:20.10.2006 / 21.01.2013

Expiration Date:Unlimited

The owner of the registration certificate:ESKOM NPK, OAO ESKOM NPK, OAO Russia

Manufacturer: & nbsp

ESKOM NPK, OAO Russia

Information update date: & nbsp21.03.2017

Illustrated instructions

Instructions

Hemodez-H (Haemodes-N)