Hemodez-H (Haemodes-N)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substancePotassium Chloride + Calcium Chloride + Magnesium Chloride + Sodium Hydrocarbonate + Sodium Chloride + Povidone-8 Thousand.Potassium Chloride + Calcium Chloride + Magnesium Chloride + Sodium Hydrocarbonate + Sodium Chloride + Povidone-8 Thousand.
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    • Dosage form: & nbspsolution for infusions
    Composition:Povidone (low molecular weight polyvinylpyrrolidone medical 8000 ± 2000 for the preparation of Hemodez-H) in terms of anhydrous - 60 g; sodium chloride - 5.50 g: potassium chloride - 0.42 g;calcium chloride hexahydrate 0.50 g: magnesium chloride hexahydrate 0.005 g: sodium bicarbonate 0.23 g; water for injection - up to 1 liter.
    Description:

    Transparent liquid of light yellow or yellow color.

    Pharmacotherapeutic group:Detoxifying agent
    ATX: & nbsp

    B.05.A.A   Blood plasma preparations and plasma-substituting drugs

    Pharmacodynamics:

    The action of Hemodeza-H is due to the ability of low-molecular-weight polyvinylpyrrolidone to bind toxins circulating in the blood and to rapidly remove them from the body. Hemodez-H differs from Hemo deza by a lower molecular weight of polyvinylpyrrolidone. The decrease in the molecular weight of the polymer accelerates the excretion of it by the kidneys from the body and improves the detoxification properties of the preparation. It increases renal blood flow, increases glomerular filtration and increases diuresis.

    Pharmacokinetics:Metabolic transformations in the body are not affected. Quickly excreted by the kidneys, within 4 hours 80% is output, and after 12 - 24 hours - completely.
    Indications:

    Shock (post-traumatic, postoperative, burn, hemorrhagic), intoxication (toxic diseases of the gastrointestinal tract: dysentery, dyspepsia,salmonellosis); as a means of detoxification in the postoperative period; peritonitis; liver disease, accompanied by the development of chronic insufficiency; intestinal obstruction; thyrotoxicosis; burn disease; acute radiation sickness, sepsis, pneumonia; acute phase of infarction. myocardium; hemolytic disease of newborns; intrauterine infection and toxemia of newborns; Toxicosis of pregnant women.

    Contraindications:

    Hypersensitivity to the drug, intracranial hypertension, hemorrhagic stroke, condition after craniocerebral trauma, cardiovascular insufficiency IIb - III degree, respiratory failure, severe allergic reactions, thromboembolism, oliguria, anuria, acute nephritis, bronchial asthma, phlebothrombosis.

    Carefully:Not described.
    Pregnancy and lactation:Not described.
    Dosing and Administration:

    Intravenously drip at a speed of 40 to 80 drops per minute, through a device with a filter.

    The dose depends on the age of the patient and the severity of intoxication.

    Single dose for adults - from 200 to 500 ml; for children from 5 to 10 ml / kg. The maximum single dose for infants is 50 to 70 ml; at the age from 2 to 5 years - 100 ml; from 5 to 10 years - 150 ml; from 10 to 15 years - 200 ml.

    The drug is administered once or repeatedly (up to 2 times a day) for 1 to 10 days, depending on the severity of intoxication. In acute gastrointestinal infections, burn and radiation sickness is administered from 1 to 2 times a day; with hemolytic disease and toxemia of newborns - from 2 to 8 times a day (daily or every other day); with large focal myocardial infarction (on the first day) - 200 ml once, with complications on the second day - 200 ml.

    Side effects:

    With the slow introduction of Haemodesum-H, complications do not usually arise. Introduction with increased speed can cause a decrease in blood pressure, tachycardia, difficulty breathing and require the introduction of vasoconstrictor and cardiac agents, calcium chloride. Individual patients may experience allergic reactions, up to the development of anaphylactic shock. In these cases, the infusion should be stopped immediately, symptomatic therapy should be administered (antigistamines, cardiotonic drugs, glucocorticoids, vasopressic drugs).

    Overdose:

    In case of an overdose, the drug should be withdrawn and symptomatic therapy should be performed.

    Interaction:Not described.
    Special instructions:

    With extensive burns combined with the introduction of plasma, albumin, gammaglobulin.

    Before starting the infusion, the doctor must check the integrity and integrity of the package. The drug should be clear, free of sediment, sediment and mold. The results of visual inspection are recorded in the medical history. Before administration, the solution is warmed to body temperature.
    Effect on the ability to drive transp. cf. and fur:Not described.
    Form release / dosage:

    Solution for infusion.

    Packaging:

    200 ml or 400 ml in glass bottles for blood, transfusion and infusion drugs.

    1 bottle with instructions for use in pack of cardboard.

    For 20, 24 or 28 bottles of capacity 250 ml or 15 bottles of capacity 450 ml with an equal number of copies instructions for use in the car boxtonne with partitions (for hospitals).

    Storage conditions:

    At a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Freezing of the drug provided seal the bottle, and non-wetting of the inner surface of it walls are not grounds for rejecting its application.

    Shelf life:

    2 years. Do not use after the expiration date.

    Terms of leave from pharmacies:On prescription
    Registration number:LSR-001581/08
    Date of registration:14.03.2008 / 09.04.2015
    Expiration Date:Unlimited
    The owner of the registration certificate:Kursk Biofactory - BIOK, FKPKursk Biofactory - BIOK, FKP Russia
    Manufacturer: & nbsp
    Information update date: & nbsp21.03.2017
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