Hemodez-8000 (Haemodes-8000)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
Read on
Active substancePotassium Chloride + Calcium Chloride + Magnesium Chloride + Sodium Hydrocarbonate + Sodium Chloride + Povidone-8 Thousand.Potassium chloride + Calcium chloride + Magnesium chloride + Sodium bicarbonate + Sodium chloride +Povidone-8 thousand.
Similar drugsTo uncover
  • Hemodez-8000
    solution d / infusion 
    BIOSINTEZ, PAO     Russia
  • Hemodez-H
    solution d / infusion 
    MAKSFARM, OJSC     Russia
  • Hemodez-H
    solution d / infusion 
    MOSFARM, LLC    
  • Hemodez-H
    solution d / infusion 
    ESKOM NPK, OAO     Russia
  • Hemodez-H
    solution d / infusion 
    MOSHIMFARM PREPARATES them. N.А.Semashko, OJSC     Russia
  • Hemodez-H
    solution d / infusion 
    Kursk Biofactory - BIOK, FKP     Russia
  • Hemodez-H
    solution d / infusion 
    RESTER, CJSC     Russia
  • Hemodez-H
    solution d / infusion 
    ELFARMI, LTD.     Russia
  • Hemodez-H
    solution d / infusion 
    PHARMSTANDART-UFIM VITAMIN FACTORY, OJSC     Russia
  • Hemodez-H
    solution d / infusion 
    DALHIMFARM, OJSC     Russia
  • Hemodez-H
    solution d / infusion 
    ATOLL, LLC     Russia
  • Krasgemodez 8000
    solution d / infusion 
    BIOSINTEZ, PAO     Russia
  • Krasgemodez 8000
    solution d / infusion 
    KRASFARMA, JSC     Russia
  • Neohemodes
    solution in / in 
    SYNTHESIS, OJSC     Russia
  • Neohemodes
    solution inwards 
    FIRM MEDPOLIMER, JSC     Russia
    • Dosage form: & nbsp
    RAster for infusions
    Composition:

    Per one liter:

    Active substances:


    Povidone (low molecular weight polyvinylpyrrolidone 8000 ± 2000)

    60 grams

    Sodium chloride

    5.50 g

    Calcium chloride hexahydrate

    0.50 g

    Potassium chloride

    0.42 g

    Sodium bicarbonate

    0.23 g

    Magnesium chloride hexahydrate

    0.005 g

    Excipient:


    Water for injections

    up to 1 liter
    Description:Transparent liquid of light yellow or yellow color.
    Pharmacotherapeutic group:Detoxifying agent
    ATX: & nbsp

    B.05.A.A   Blood plasma preparations and plasma-substituting drugs

    Pharmacodynamics:

    The effect of the drug is due to the ability of low molecular weight polyvinylpyrrolidone to bind toxins circulating in the blood and quickly remove them from the body. The most fully binds toxins circulating in the blood of patients with dysentery, salmonella, food intoxication. With burn disease, the toxins formed in the first 4-5 days of the disease are almost completely inactivated; toxins formed at a later date are much less neutralized.

    Toxins formed in the body of patients with acute radiation sickness do not bind, although it is possible to accelerate their excretion from the body.

    The drug contributes to the elimination of stasis of erythrocytes in capillaries, developing with intoxication of any origin, which leads to an improvement in microcirculation.It enhances kidney blood flow, increases glomerular filtration and increases diuresis.

    The drug is non-toxic, does not have antigenic and pyrogenic properties.

    The decrease in the molecular weight of the polymer accelerates the excretion of it by the kidneys from the body and improves the detoxification properties of the preparation.
    Pharmacokinetics:

    Metabolism in the body is not affected. Quickly excreted by the kidneys, within 4 hours - 80%, after 12-24 h - completely.

    Indications:

    As a detoxifying drug: toxic forms of gastrointestinal diseases (including Shigella, Salmonella, dyspepsia); peritonitis, intestinal obstruction (in the pre- or postoperative period); sepsis, burn disease at the stage septicopyemia, exogenous poisoning in stage of toxemia.

    Contraindications:

    Hypersensitivity, intracranial hypertension, hemorrhagic stroke, post-traumatic brain injury, chronic heart failure IIb)III degree, respiratory insufficiency, severe allergic reactions, thromboembolism, oliguria, anuria, acute nephritis, asthma, phlebothrombosis, lactation.

    Carefully:

    Pregnancy.

    Pregnancy and lactation:

    During pregnancy, the drug is used if the benefit to the mother exceeds the possible risk to the fetus.

    During the use of the drug, breastfeeding should be discontinued.

    Dosing and Administration:

    Intravenously drip (40-80 cap / min).

    The dose depends on the age of the patient and the severity of intoxication.

    Single dose for adults and children over 15 years of age - 200-500 ml; for children under 15 years - 2.5 ml / kg. The maximum single dose for children under 2 years is 70 ml, 2-5 years - 100 ml, 6-9 years - 150 ml, 10-15 years - 200 ml.

    Enter 1-2 times a day for 1-10 days.

    Side effects:

    Reduced blood pressure, tachycardia, difficulty breathing (with rapid administration), allergic reactions of varying severity (up to the development of anaphylactic shock).

    Infection at the injection site, thrombosis or phlebitis, spreading from the site of infusion.

    Overdose:

    In case of an overdose, the drug should be withdrawn and symptomatic therapy should be performed.

    Interaction:

    Drug interaction of the drug is not described.

    Special instructions:

    With extensive burns combined with the introduction of plasma, albumin, gamma globulin.

    Before the start of the infusion, it is necessary to check the expiry date of the package.The drug should be clear, free of sediment, sediment and mold. Pressing the container with the preparation is checked for its tightness and the integrity of the package. The results of visual inspection are recorded in the medical history.

    During the treatment, it is necessary to monitor blood pressure and the patient's condition.

    Before administration, the solution is warmed to body temperature.

    Effect on the ability to drive transp. cf. and fur:

    Studies to evaluate the effect of the drug on the ability to drive vehicles and engage in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions have not been conducted.

    Form release / dosage:

    Solution for infusion.

    Packaging:

    200 ml or 400 ml in a glass bottle, corked with a rubber stopper and crimped with an aluminum cap or a combination cap.

    1. A bottle with instructions for use is placed in a pack of cardboard.

    2. For hospitals. 20, 24 bottles of 200 ml or 12 bottles of 400 ml with an equal number of instructions for use, placed in a group box - boxes of cardboard corrugated.

    250 ml or 500 ml in a soft polymer container.

    1.Each container with instructions for use is packaged in a secondary bag of film, the bag is sealed. It is allowed to apply the text of the instruction for medical use thermographically to a secondary bag (the instruction is not included in the secondary bag).

    24 containers of 250 ml or 12 containers of 500 ml, sealed in secondary bags, placed in a group box - boxes of corrugated cardboard.

    2. Each container is packed in a secondary bag of film, the bag is sealed. A self-adhesive multi-page label is glued onto the bag.

    24 containers of 250 ml or 12 containers of 500 ml, sealed in secondary bags, placed in a group box - boxes of corrugated cardboard.

    3. For hospitals. Each container is packed in a secondary bag of film, the bag is sealed.

    24 containers of 250 ml or 12 containers of 500 ml sealed in secondary bags, with an equal number of instructions for use, are placed in a group box - boxes of cardboard corrugated.

    Storage conditions:

    At a temperature of no higher than 25 ° C.

    Single and repeated freezing at temperatures up to minus 45 ° C does not affect the quality of the drug.

    Non-wetting of the inner surface of the bottle (container) is not a contraindication to the use of the drug.

    Shelf life:

    3 years.

    Do not use after the expiration date.

    Terms of leave from pharmacies:On prescription
    Registration number:P N000671 / 01
    Date of registration:12.05.2011 / 21.05.2014
    Expiration Date:Unlimited
    The owner of the registration certificate:BIOSINTEZ, PAO BIOSINTEZ, PAO Russia
    Manufacturer: & nbsp
    Information update date: & nbsp21.03.2017
    Illustrated instructions
      Instructions
      Up