Glycerin - instructions for use, dose, side effects, contraindications

active substance: glycerol (glycerol) - 1.24 or 2.11 g in terms of 100% glycerol content (corresponding to 1.32 g or 2.25 g 94% glycerol with a density of not less than 1.2481 g / cm);

Excipients: macrogol 400 (polyethylene oxide 400) - 0.12 g or 0.21 g; stearic acid - 0.12 g or 0.205 g; sodium carbonate decahydrate (sodium carbonate 10-water) 0.060 g or 0.103 g.

Description:Suppositories are transparent or translucent, almost colorless or with a yellowish-brown tinge, with an abrasion surface, hygroscopic, torpedo-shaped.

Suppository clouding, slight softening of the surface layer and fogging of the contoured package are allowed.

Suppositories are uniform in longitudinal section. The air rod is allowed on the cut.

Pharmacotherapeutic group:Laxative

ATX: & nbsp

A.06.A.X.01 Glycerol

Pharmacodynamics:

Laxative.

When used in the form of rectal suppositories softens and lubricates hardened fecal masses, facilitates their passage through the large intestine, irritates the mucosa of the intestine,reflexively stimulating intestinal motility, initiate the process of defecation, facilitates the passage and excretion of stool.

Pharmacokinetics:

It is actively metabolized in the liver. It is excreted through the kidneys, 7-14% are unchanged.

Indications:

Symptomatic treatment of constipation of various etiologies (when the use of oral medications is impossible).

Prevention of constipation in patients who can not strain during defecation: painful thrombosed hemorrhoids, anal fissures or perianal abscess, anorectal stenosis, after a myocardial infarction.

Contraindications:

Hypersensitivity to glycerol or any of the components of the drug.

Irritable bowel syndrome, intestinal obstruction, appendicitis, bleeding, diarrhea, hemorrhoids in the acute stage, fissures of the anus, inflammatory diseases and rectal tumors, undiagnosed abdominal pain, hemorrhagic rectocolitis, children under 5 years.

Carefully:

Renal failure.

Pregnancy and lactation:

During pregnancy and during breastfeeding, the drug can be used only if the expected benefit to the mother exceeds the potential risk to the fetus.

It is not known whether glycerin is excreted into breast milk, so this drug is used only if, in the opinion of the doctor, the expected benefit to the mother exceeds the potential risk for the child.

Dosing and Administration:

Rectally.

Enter the drug into the rectum and leave there for at least 5 minutes. Usually defecation occurs through 5-10 minutes after the administration of the agent. The remains of the suppository are removed from the intestine with feces.

Children from 5 to 12 years appoint 1 suppository containing 1.24 g of glycerol, once a day.

Children over 12 years and adults prescribe 1 suppository, containing 2.11 g of glycerol, once a day. If necessary, increase the dose to 2 suppositories per day.

Features of the drug during the first admission or when it is canceled

There is no information.

Side effects:

With prolonged use, it is possible to weaken the physiological process of defecation.

Allergic reactions, local reactions (itching, burning in the anus), the appearance of spasmodic pain in the intestine.

If side effects develop, consult a doctor.

Overdose:

Symptom of overdose is frequent loose stools.

In case of an overdose, the drug should be discontinued.

Interaction:There is no information.

Special instructions:

Before and after using suppositories, you should thoroughly wash your hands.

Systematic reception is not recommended.

Treatment is discontinued after restoration of normal intestinal peristalsis.

It is not recommended to use suppositories for longer than 1 week.

Do not lubricate the suppository with mineral liquid or solid oils.

Effect on the ability to drive transp. cf. and fur:

There is no information.

Form release / dosage:

Suppositories rectal, 1,24 or 2,11 g.

Packaging:

There are 5 suppositories in a contiguous cell package.

Two contour mesh packs, along with instructions for medical use of the drug, are placed in a pack of cardboard.

Storage conditions:

At a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

2 years.

Do not use after the expiration date indicated on the label.

Terms of leave from pharmacies:Without recipe

Registration number:LP-003503

Date of registration:14.03.2016

Expiration Date:14.03.2021

The owner of the registration certificate:TULA PHARMACEUTICAL FACTORY, LTD. TULA PHARMACEUTICAL FACTORY, LTD. Russia

Manufacturer: & nbsp

TULA PHARMACEUTICAL FACTORY, LTD. Russia

Representation: & nbspTULA PHARMACEUTICAL FACTORY, LTD.TULA PHARMACEUTICAL FACTORY, LTD.

Information update date: & nbsp30.04.2017

Illustrated instructions

Instructions

Glycerol (Glycerin)