Glycerin Suppositories (Glycerin suppositoiums)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceGlycerolGlycerol
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    • Dosage form: & nbsprectal suppositories
    Composition:
    1 suppository 1405 mg contains:
    active substance: glycerol - 1405 mg;
    Excipients: Sodium stearate - 95 mg, purified water - 80 mg.
    1 suppository 2100 mg contains:
    active substance: glycerol - 2100 mg;
    Excipients: Sodium stearate - 140 mg, purified water - 120 mg.
    Description:

    Suppositories torpedo-shaped, translucent, almost colorless with a weak yellowish tinge, with an oily smooth surface, with a weak characteristic odor.

    Pharmacotherapeutic group:Laxative
    ATX: & nbsp

    A.06.A.X.01   Glycerol

    Pharmacodynamics:

    Laxative.

    When used in the form of rectal suppositories, it softens and lubricates hardened fecal masses, facilitates their passage through the large intestine, irritates the intestinal mucosa, reflexively stimulates intestinal motility, initiates the process of defecation, facilitates the passage and excretion of stool.

    Pharmacokinetics:

    Well absorbed through the mucosa of the rectum.It is actively metabolized in the liver. It is excreted through the kidneys, 7-14% are unchanged.

    Indications:

    Symptomatic treatment of constipation of various etiologies (when the use of oral medications is impossible).

    Prevention of constipation in patients who can not strain during defecation: painful thrombosed hemorrhoids, anal fissures or perianal abscess, anorectal stenosis, after a myocardial infarction.

    Contraindications:

    Hypersensitivity to glycerol or any of the components of the drug.

    Irritable bowel syndrome, intestinal obstruction, appendicitis, bleeding, diarrhea, hemorrhoids in the acute stage, fissures of the anus, inflammatory diseases and rectal tumors, undiagnosed abdominal pain, hemorrhagic rectocolitis, children under 5 years.

    Carefully:

    Renal failure.

    Pregnancy and lactation:

    During pregnancy and lactation, the drug can be used only if the expected benefit to the mother exceeds the potential risk to the fetus.

    It is not known whether glycerin is excreted into breast milk, so this medication is used only if,according to the doctor, the expected benefit for the mother exceeds the potential risk to the fetus.

    Dosing and Administration:

    Rectally, 15-20 minutes after breakfast.

    Enter the drug into the rectum and leave there for at least 5 minutes. Usually, defecation occurs 5-10 minutes after the administration of the drug. The remains of the suppository are removed from the intestine with feces.

    Children from 5 to 12 years are prescribed 1 suppository, containing 1405 mg of glycerol, once a day.

    Children over 12 years and adults are prescribed 1 suppository, containing 2100 mg of glycerol, once a day. If necessary, increase the dose to 2 suppositories per day.

    Side effects:

    Allergic reactions, local reactions (itching, burning in the anus), the appearance of spasmodic pain in the intestine. It passes by itself after drug discontinuation

    With prolonged use, irritation of the rectum, weakening of the physiological process of defecation are possible.

    Overdose:

    Symptom of overdose is frequent loose stools. In case of an overdose, the drug should be discontinued.

    Interaction:No data.
    Special instructions:

    Use with caution in case of impaired renal function, allergies, nausea, vomiting.Before and after using suppositories, you should thoroughly wash your hands. Systematic reception is not recommended. Treatment is discontinued after restoration of normal intestinal peristalsis. It is not recommended to use suppositories for longer than 1 week.

    Do not lubricate the suppository with mineral liquid or solid oils.

    Effect on the ability to drive transp. cf. and fur:

    Not installed.

    Form release / dosage:

    Suppositories rectal 1405 mg and 2100 mg.

    Packaging:

    Primary packaging

    By 6 suppositories in a contour mesh package made of aluminum foil, dubbed with polyethylene film.

    Secondary packaging

    For 1 or 2 contour packs with instructions for medical use in a pack of cardboard.

    Storage conditions:

    Store at a temperature not exceeding 25 ° C. Keep out of the reach of children.

    Shelf life:

    3 years.

    Do not use after the expiration date printed on the package.

    Terms of leave from pharmacies:Without recipe
    Registration number:LP-002498
    Date of registration:16.06.2014
    Expiration Date:16.06.2019
    The owner of the registration certificate:BOPHARM, OJSC BOPHARM, OJSC Russia
    Manufacturer: & nbsp
    Representation: & nbspBopharm OJSCBopharm OJSCRussia
    Information update date: & nbsp30.04.2017
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