Glycerol (Glycerin)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
Read on
Active substanceGlycerolGlycerol
Similar drugsTo uncover
  • Glycelax®
    suppositories rect. 
    MOSCOW PHARMACEUTICAL FACTORY, CJSC     Russia
  • Glycerol
    solution externally 
    PHARMACEUTICAL FACTORY of St. Petersburg, JSC     Russia
  • Glycerol
    solution externally 
    ECOLAB, CJSC     Russia
  • Glycerol
    solution externally 
    TULA PHARMACEUTICAL FACTORY, LTD.     Russia
  • Glycerol
    solution locally externally 
    MUROMSKY INSTRUMENT-MAKING PLANT, OJSC     Russia
  • Glycerol
    solution externally 
    PERMFARMACY, OJSC     Russia
  • Glycerol
    solution locally externally 
    KEMEROVSKAYA PHARMACEUTICAL FACTORY, OJSC     Russia
  • Glycerol
    solution locally externally 
    SAMARAHEDPROM, JSC     Russia
  • Glycerol
    solution locally externally 
    LASKRAFT, CJSC     Russia
  • Glycerol
    solution externally 
    TVERSKAYA PHARMACEUTICAL FACTORY, OJSC     Russia
  • Glycerol
    suppositories rect. 
    NIZHFARM, JSC     Russia
  • Glycerol
    solution locally externally 
    PHARMSTANDART-PHYTOPHARM-NN, LLC     Russia
  • Glycerol
    solution locally externally 
    KAZAN PHARMACEUTICAL FACTORY, CJSC     Russia
  • Glycerol
    solution externally 
    YAROSLAVSK PHARMACEUTICAL FACTORY, CJSC     Russia
  • Glycerol
    suppositories rect. 
    TULA PHARMACEUTICAL FACTORY, LTD.     Russia
  • Glycerol
    suppositories rect. 
    Pharmex Group, LLC     Ukraine
  • Glycerol
    suppositories rect. 
    YUZHFARM, LLC     Russia
  • Glycerin Suppositories
    suppositories rect. 
    BOPHARM, OJSC     Russia
  • Dexeril®
    cream externally 
    Pierre Fabre Dermatology     France
    • Dosage form: & nbsprectal suppositories
    Composition:

    1 suppository 2.63 g contains:

    Active substance: glycerol - 2,630 g.

    Excipients: sodium carbonate decahydrate 0.096 g, stearic acid - 0.230 g, macrogol 400 - 0.394 g

    1 suppository 0.88 g contains:

    Active substance: glycerol - 0.880 g.

    Excipients: sodium carbonate decahydrate - 0.032 g, stearic acid - 0.077 g, macrogol 400 0.132 g

    Description:

    Suppositories are transparent or translucent, almost colorless or with a faint yellowish tinge, with a smearing surface, hygroscopic, torpedo-shaped. It is possible to have a funnel-shaped depression, opacification cloudiness, slight softening of the surface layer, condensation on the package.

    Pharmacotherapeutic group:Laxative
    ATX: & nbsp

    A.06.A.X.01   Glycerol

    Pharmacodynamics:

    Laxative.

    When used in the form of rectal suppositories softens and lubricates hardened fecal masses, facilitates their passage through the large intestine, exerts an irritating effect on the intestinal mucosa,reflexively stimulates intestinal motility, initiate the process of defecation, facilitates the passage and excretion of stool.

    Pharmacokinetics:

    Well absorbed through the mucosa of the rectum. It is actively metabolized in the liver. It is excreted through the kidneys, 7-14% are unchanged.

    Indications:

    Symptomatic treatment of constipation of various etiologies (when the use of oral medications is impossible).

    Prevention of constipation in patients who can not strain during defecation: painful thrombosed hemorrhoids, anal fissures or perianal abscess, anorectal stenosis, after a myocardial infarction.

    Contraindications:

    Hypersensitivity to glycerol or any of the components of the drug.

    Irritable bowel syndrome, intestinal obstruction, appendicitis, bleeding, diarrhea, hemorrhoids in the acute stage, anal fissures, inflammatory diseases and rectal tumors, undiagnosed abdominal pain, hemorrhagic rectoculitis, children under 1 year.

    Carefully:Pkidney failure.
    Pregnancy and lactation:

    During pregnancy and lactation, the drug can be used only if the expected benefit to the mother exceeds the potential risk to the fetus.

    It is not known whether glycerin is excreted into breast milk, so this medication is used only if, in the opinion of the doctor, the expected benefit to the mother exceeds the potential risk to the fetus.

    Dosing and Administration:

    Rectally.

    Enter the drug into the rectum and leave there for at least 5 minutes. Usually, defecation occurs 5-10 minutes after the administration of the drug. The remains of the suppository are removed from the intestine with feces.

    Children over 12 years and adults prescribe 1 suppository, containing 2.63 g of glycerol, once a day. If necessary, increase the dose to 2 suppositories per day.

    Children from 1 to 12 years old prescribe 1 suppository containing 0.88 g of glycerol, once a day.

    Side effects:

    Allergic reactions, local reactions (itching, burning in the anus), the appearance of spasmodic pain in the intestine.

    With prolonged use, irritation of the rectum, weakening of the physiological process of defecation are possible.

    If any of the side effects listed in the manual are aggravated,or any other side effects not listed in the instructions are noted, the doctor should be informed immediately.

    Overdose:

    Symptoms: frequent loose stools.

    Treatment: cancellation of the drug. Symptomatic treatment.

    Interaction:

    Data on interactions with other drugs are not available.

    Special instructions:

    Use with caution in case of impaired renal function, allergies, nausea, vomiting.

    Before and after using suppositories, you should thoroughly wash your hands.

    Systematic reception is not recommended.

    Treatment is discontinued after restoration of normal intestinal peristalsis.

    It is not recommended to use suppositories for longer than 1 week.

    Do not lubricate the suppository with mineral liquid and solid oils.

    Effect on the ability to drive transp. cf. and fur:

    Not installed.

    Form release / dosage:

    Suppositories rectal, 0.88 g and 2.63 g.

    Packaging:

    For 5 suppositories in a PVC / PVDC / PE strip.

    For 1 or 2 strips together with instructions for use in a pack of cardboard.

    Storage conditions:

    In the original packaging, at a temperature of 2 to 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    2 years.

    Do not use the drug after the expiration date.

    Terms of leave from pharmacies:Without recipe
    Registration number:LP-004052
    Date of registration:29.12.2016
    Expiration Date:29.12.2021
    The owner of the registration certificate:Pharmex Group, LLCPharmex Group, LLC Ukraine
    Manufacturer: & nbsp
    Representation: & nbspAlfa Grand TD, LLCAlfa Grand TD, LLCRussia
    Information update date: & nbsp30.04.2017
    Illustrated instructions
      Instructions
      Up