Active substanceTaurineTaurine
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  • Dosage form: & nbsppills
    Composition:

    Active component: taurine - 500 mg.

    Auxiliary components: povidone - 57.0 mg, microcrystalline cellulose - 18.0 mg, croscarmellose sodium - 17.2 mg, calcium stearate - 4.8 mg, silicon dioxide colloid - 3.0 mg.

    Description:Tablets are white or almost white in color, round, flat-cylindrical with a risk and a facet.
    Pharmacotherapeutic group:Metabolic means
    ATX: & nbsp

    S.01.X.A   Other drugs for the treatment of eye diseases

    C.01.E.B   Other drugs for the treatment of heart disease

    Pharmacodynamics:

    Taurine is a natural product of the exchange of sulfur-containing amino acids: cysteine, cysteamine, methionine. Taurine has osmoregulatory and membrane-protective properties, positively affects the phospholipid composition of cell membranes, normalizes the exchange of calcium and potassium ions in cells. In taurine, the properties of the inhibitory neurotransmitter are revealed, it possesses anti-stress action, it can regulate the release of gamma-aminobutyric acid (GABA), adrenaline, prolactin and other hormones, and regulate responses to them. By participating in the synthesis of respiratory chain proteins in mitochondria, taurine regulates oxidative processes and exhibits antioxidant properties; affects enzymes such as cytochromes, involved in the metabolism of various xenobics.

    Taurine improves metabolic processes in the heart, liver and other organs and tissues.In chronic diffuse liver disease taurine increases blood flow and reduces the severity of cytolysis.

    Treatment with CardioActiv®

    Taurine in cardiovascular insufficiency (CVS) leads to a reduction in stagnant phenomena in small and large circles of the circulation: intracardiac diastolic pressure decreases, myocardial contractility increases (maximum rate of contraction and relaxation, indices of contractility and relaxation). The drug moderately reduces blood pressure (BP) in patients with hypertension and has virtually no effect on blood pressure in patients with cardiovascular failure with low blood pressure.

    Cardio Active® Taurine reduces side effects that occur when an overdose of cardiac glycosides and blockers of "slow" calcium channels; reduces the hepatotoxicity of antifungal agents. Increases working capacity in severe physical exertion.

    At a diabetes approximately in 2 weeks after the beginning of reception of a preparation Kardioaktiv® Taurine decreases the concentration of glucose in the blood. There was also a significant decrease in the concentration of triglycerides, to a lesser extent - the concentration of cholesterol, a decrease in the atherogenicity of plasma lipids.With prolonged use of the drug (about 6 months), improvement of the microcirculatory blood flow of the eye was noted. Taurine improves metabolic processes in the heart, liver and other organs and tissues.

    In chronic diffuse liver disease taurine increases blood flow and reduces the severity of cytolysis.

    Pharmacokinetics:

    After a single oral intake of 500 mg of CardioActiv® Taurine, active substance taurine After 15-20 minutes it is determined in the blood, reaching a maximum after 1.5-2 hours. Completely the drug is withdrawn after 24 hours.

    Indications:

    The drug is used in complex therapy:

    - cardiovascular insufficiency of different etiology;

    - intoxication caused by the intake of cardiac glycosides;

    - Type 1 diabetes mellitus;

    Type 2 diabetes mellitus, including moderate hypercholesterolemia.
    Contraindications:

    Severe heart failure in decompensation.

    Hypersensitivity to the drug.

    Cardio Active® Taurine is not recommended for use in children under the age of 18 due to inadequate data on efficacy and safety.

    Carefully:

    Use with caution in patients with severe impairment of renal function, with simultaneous use with cardiac glycosides, blockers of "slow" calcium channels (BCCC).

    Pregnancy and lactation:

    It is not recommended to use CardioActiv® Taurine during pregnancy and during breastfeeding due to the lack of sufficient clinical experience in this category of patients.

    Dosing and Administration:

    Before using the drug, consult a doctor.

    In heart failure CardioActiv® Taurine take inside 250-500 mg (1/2 - 1 tablet) 2 times a day for 20 minutes before meals, the course of treatment - 30 days. The dose can be increased to 2-3 g (4-6 tablets) per day.

    In case of cardiac glycoside intoxication - not less than 750 mg (1.5 tablets) per day.

    In type 1 diabetes, 500 mg (1 tablet) 2 times a day in combination with insulin therapy for 3-6 months.

    In type 2 diabetes, 500 mg (1 tablet) 2 times a day in combination with diet therapy or other hypoglycemic agents for oral administration.

    In type 2 diabetes mellitus, including with moderate hypercholesterolemia, 500 mg (1 tablet) 2 times a day.

    Side effects:

    Allergic reactions to the components of the drug are possible.

    Overdose:Data on overdose are absent.
    Interaction:

    Cardio Active® Taurine can be used with other medicines.

    Taurine enhances the inotropic effect of cardiac glycosides.

    Special instructions:

    In the complex treatment of heart failure, diabetes, intoxication with cardiac glycosides, the drug is administered under the supervision of a doctor.

    Effect on the ability to drive transp. cf. and fur:

    The drug does not affect the performance of potentially hazardous activities requiring increased concentration of attention and speed of psychomotor reactions (vehicle management, work with moving mechanisms, dispatcher, operator, etc.).

    Form release / dosage:

    Tablets 500 mg.

    Packaging:For 20 tablets in a contour mesh package made of a polyvinylchloride film and flexible packaging made on the basis of aluminum foil. For 2 or 3 contour squares, together with the instruction for use, they are placed in a pack of cardboard.
    Storage conditions:

    Store at a temperature not exceeding 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    3 years.

    Do not use after the expiration date.

    Terms of leave from pharmacies:Without recipe
    Registration number:LP-002686
    Date of registration:29.10.2014
    Expiration Date:29.10.2019
    The owner of the registration certificate:EVALAR, CJSC EVALAR, CJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp10.12.2017
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