Taurine - instructions for use, dose, side effects, contraindications

Amino acid containing sulfur. It is formed in the body from cysteine, is included in the exchange of lipids, which form part of cell membranes, normalizes the electrolyte composition of cells due to retention of calcium and potassium ions.It takes part in the emulsification of fats, as it is part of taurocholic and taurodeoxycholic bile acid. As a neurotransmitter of the central nervous system, it inhibits synaptic transmission in the brain, has moderate anticonvulsant activity. Normalizes the metabolism of eye tissues in dystrophic processes and traumatic injuries.

Pharmacokinetics:

After oral administration, it is completely absorbed in the gastrointestinal tract. The maximum concentration in the blood plasma is achieved after 1.5-2 hours.

The half-life is 6 hours. Elimination by the kidneys.

When topical application is not absorbed and does not have a systemic effect.

Indications:

As a local remedy is used to treat the dystrophic processes of the mesh shell of the eyes, cataracts, and trauma to the cornea. Used in composition of complex therapy for intoxication with cardiac glycosides, diabetes mellitus I and II type.

ICD-10

IV.E10-E14.E10 Insulin-dependent diabetes mellitus

IV.E10-E14.E11 Non-insulin-dependent diabetes mellitus

VII.H15-H22.H18.4 Degeneration of the cornea

VII.H25-H28.H25 Star cataract

VII.H25-H28.H26.1 Traumatic cataract

VII.H25-H28.H26.8 Other specified cataract

VII.H25-H28.H28.0 * Diabetic cataract (E10-E14 + with common fourth sign .3)

VII.H30-H36.H35.3 Degeneration of the macula and posterior pole

IX.I30-I52.I50.9 Heart failure, unspecified

XIX.S00-S09.S05 Injury of the eye and orbit

XIX.T36-T50.T46.0 Poisoning with cardiac glycosides and preparations of similar action

IX.I30-I52.I50.0 Congestive heart failure

Contraindications:

Individual intolerance, children under 18 years.

Carefully:

Hypersensitivity.

Pregnancy and lactation:

Recommendations for FDA - Category B. It is used during pregnancy and lactation.

Dosing and Administration:

Inside, 250-500 mg 2 times a day. If necessary, the dose increases to 2-3 g per day.

Locally: instillation in the conjunctival bag 2-3 drops 2-4 times a day for 3 months, followed by repeated courses at intervals of 1 month.

Subconjunctival: 0.3 ml of a 4% solution once a day for 10 days, with a repeated course after 6 months.

The highest daily dose: 3 g.

The highest single dose: 500 mg.

Side effects:

Allergic reactions.

Overdose:

Cases of overdose are not described.

Treatment is symptomatic.

Interaction:

Clinically significant interactions are not described.

Special instructions:

Taurine can be used for glaucoma.

Instructions

Taurine (Taurinum)