Active substanceLevomenthol solution in menthil isovalerateLevomenthol solution in menthil isovalerate
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  • Dosage form: & nbspcapsules for oral hygiene
    Composition:

    Per one capsule:

    Active substance: levomenthol solution in menthyl isovalerate - 100.00 mg;

    Excipients: alpha-tocopherol acetate (vitamin E) - 0.45 mg, refined olive oil - q. s. up to 160,00 mg;

    Gelatin capsule shell: gelatin - 72,0000 mg, purified water - 56,2384 * mg, glycerol - 31,5216 mg, methylparahydroxybenzoate (E 218) - 0,2400 mg.

    * The amount of water to be purified is indicated.Water partially evaporates during the production process and all the content in the finished product is less than the pledged.
    Description:Capsules soft, gelatinous, oval, from light yellow to light brownish-yellow color. The contents of the capsules are a clear, colorless or yellowish tinge oily liquid with a smell of menthol.
    Pharmacotherapeutic group:Coronarodilating agent of reflex action
    ATX: & nbsp

    C.01.E.X   Other combination drugs for the treatment of heart disease

    Pharmacodynamics:

    The drug has a sedative effect, has a moderate reflex vasodilator effect, due to irritation of sensitive nerve endings. Stimulates the production and release of enkephalins, endorphins and a number of other peptides, histamine, kinin, which actively participate in the regulation of vascular permeability and the formation of pain.

    The therapeutic effect develops approximately 5 minutes after taking the drug.
    Pharmacokinetics:

    With sublingual (under the tongue) application levomenthol absorbed from the oral mucosa. After suction levomenthol metabolized in the liver and excreted by the kidneys in the form of glucuronides.

    Indications:

    Functional cardialgia, neuroses, and also as an antiemetic for sea and air sickness.

    Contraindications:

    Hypersensitivity to the drug components, acute myocardial infarction, acute disorders of cerebral circulation, severe arterial hypotension, children under 18 years of age (efficacy and safety not established).

    Pregnancy and lactation:The use of the drug during pregnancy and during breastfeeding is possible if the expected therapeutic effect for the mother exceeds the potential risk to the fetus or child.
    Dosing and Administration:

    Kormenthol is prescribed for adults under the tongue, 1 capsule 2-3 times a day. Capsule should be kept under the tongue until it is completely resorbed. The daily frequency and duration of reception is determined depending on the effectiveness of treatment. If the therapeutic effect is not sufficiently pronounced or when the effect is not observed in individual patients within the next 5 minutes after taking the drug, it is necessary to consult a doctor.

    Side effects:

    Nausea, a feeling of discomfort in the abdomen, lacrimation, dizziness, also possible a short-term decrease in blood pressure, drowsiness. The described phenomena, as a rule, are short-lived, pass independently and do not require withdrawal of the drug.

    In rare cases, the development of allergic reactions (skin rash, itching, angioedema) is possible.

    If any of the side effects listed in the manual are aggravated, or if you notice any other side effects not listed in the instructions, tell your doctor.

    Overdose:

    Symptoms: nausea, headache, a sharp decrease in blood pressure, suppression of the central nervous system, impaired cardiac activity, increased excitability.

    Treatment: withdrawal of the drug, symptomatic therapy.

    Interaction:

    It is allowed to use the drug in combination with drugs that improve metabolic processes (vitamins, potassium and magnesium asparaginate, inosine and so forth).

    With simultaneous application can enhance the effect of antihypertensive drugs, sedative affect of psychotropic drugs, opioid analgesics, funds for general and local anesthesia, ethanol.

    Simultaneous reception with nitrates helps to reduce the headache that occurs when they are used.

    Special instructions:

    It is not recommended to drink alcohol at the same time.

    Effect on the ability to drive transp. cf. and fur:

    Due to possible side effects (dizziness, drowsiness) during drug treatment, care should be taken when driving vehicles, working with mechanisms or engaging in potentially dangerous activities requiring increased concentration and speed of psychomotor reactions.

    Form release / dosage:

    Capsules sublingual, 100 mg.

    Packaging:

    15 capsules per blister of polyvinylchloride film and aluminum foil printed lacquered.

    One blister along with the instruction for use is placed in a pack of cardboard for consumer packaging.

    Storage conditions:

    Store in the original packaging at a temperature of ns above 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    3 years.

    Do not use after the expiration date.

    Terms of leave from pharmacies:Without recipe
    Registration number:LP-003029
    Date of registration:10.06.2015
    Expiration Date:10.06.2020
    The owner of the registration certificate:GIDIMAS, CJSCGIDIMAS, CJSC Lithuania
    Manufacturer: & nbsp
    Representation: & nbspBIOSAYNS CICA LLCBIOSAYNS CICA LLCRussia
    Information update date: & nbsp04.02.2018
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