Validol (Validol)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceLevomenthol solution in menthil isovalerateLevomenthol solution in menthil isovalerate
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    • Dosage form: & nbspsublingual tablets
    Composition:

    Active substance: levomenthol solution in menthyl isovalerate (validol) 0.06 g.

    Excipients: sucrose (sugar) 1.158 g, calcium stearate monohydrate 0.005 g.

    Description:Tablets are flat-cylindrical, with a facet, white with a yellowish tint of color with greyish inclusions, with a characteristic smell of menthol.
    Pharmacotherapeutic group:Coronarodilating agent of reflex action
    ATX: & nbsp

    C.01.E.X   Other combination drugs for the treatment of heart disease

    Pharmacodynamics:

    Has a sedative effect, has a moderate reflex vasodilator effect due to irritation of sensitive nerve endings. It stimulates the production and release of enkephalins, endorphins and a number of other peptides, histamine, kinins (due to irritation of mucosal receptors), which take an active part in the regulation of vascular permeability, the formation of pain. With sublingual admission, the therapeutic effect on average occurs in 5 minutes, while up to 70% of the drug is released within 3 minutes.

    Pharmacokinetics:

    With sublingual administration levomenthol absorbed from the oral mucosa, is metabolized in the liver and excreted by the kidneys in the form of glucuronides.

    Indications:

    Functional cardialgia, neuroses, and also as an antiemetic for sea and air sickness.

    Contraindications:

    Hypersensitivity, sugarase / isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption (because the drug contains sucrose), age to 18 years.

    Carefully:

    Diabetes mellitus (the drug contains sugar).

    Pregnancy and lactation:

    The use of the drug during pregnancy and during breastfeeding is possible if the intended benefit to the mother exceeds the potential risk to the fetus or child.

    Dosing and Administration:

    Validol appoint adults to 1 tablet under the tongue until it is completely resorbed.

    Take 1 tablet 2-3 times a day. Multiplicity and duration of admission is determined depending on the effectiveness of treatment.

    In the absence or inadequacy of the therapeutic effect in the next 5-10 minutes after taking the drug, you need to see a doctor for another therapy.

    Side effects:

    Nausea, lacrimation, dizziness are possible. With the withdrawal of the drug, these side effects go away on their own.

    Perhaps the development of allergic reactions (skin rash, itching, angioedema).

    Overdose:

    Symptoms: nausea, headache, a sharp decrease in blood pressure, suppression of the central nervous system, a violation of cardiac activity, a state of arousal.

    Treatment: withdrawal of the drug, symptomatic therapy.

    Interaction:

    When used simultaneously with drugs that depress the central nervous system, enhances the effect of the latter.

    The simultaneous use of Validol with nitrates reduces the headache that occurs when they are used.

    Special instructions:

    It is not recommended to drink alcohol at the same time.

    Use with caution in patients with diabetes mellitus (the drug contains sucrose). The amount of sucrose in 1 tablet corresponds to 0.09 XE (bread units).

    Effect on the ability to drive transp. cf. and fur:

    During the period of taking the drug, you should be careful when driving vehicles and practicing other potentially dangerous activities that require increased concentration and speed of psychomotor reactions.

    Form release / dosage:

    Tablets are sublingual, 60 mg.

    Packaging:

    10 tablets per contour cell packaging made of polyvinylchloride film and aluminum foil.

    2 or 3 contour mesh packages together with the instruction for use are placed in a pack of cardboard for consumer containers.

    It is allowed to use contoured cell packs with an equal number of instructions for use in a carton box box (group packaging).

    Storage conditions:

    In a dry, the dark place at a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    3 years.

    Do not use after the expiration date

    Terms of leave from pharmacies:Without recipe
    Registration number:PL-000612
    Date of registration:21.09.2011 / 05.10.2016
    Expiration Date:Unlimited
    The owner of the registration certificate:MARBIOFARM, OJSC MARBIOFARM, OJSC Russia
    Manufacturer: & nbsp
    Representation: & nbspMARBIOFARM, OJSCMARBIOFARM, OJSC
    Information update date: & nbsp03.02.2017
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