Validol - instructions for use, dose, side effects, contraindications

Shell composition (in terms of absolutely dry matter): gelatin - 17 mg or 22 mg; glycerol (glycerol) - 5 mg or 8 mg; methylparahydroxybenzoate (nipagin) 0.14 mg or 0.18 mg.

Description:Soft gelatin capsules are spherical, from colorless to light yellow, filled with a transparent oily liquid with a smell of menthol.

Pharmacotherapeutic group:Coronarodilating agent of reflex action

ATX: & nbsp

C.01.E.X Other combination drugs for the treatment of heart disease

Pharmacodynamics:

Has a sedative effect, has a moderate reflex vasodilator effect due to irritation of sensitive nerve endings. It stimulates the production and release of enkephalins, endorphins and a number of other peptides, histamine, kinins (due to irritation of mucosal receptors), which take an active part in the regulation of vascular permeability, the formation of pain. With sublingual admission, the therapeutic effect on average occurs in 5 minutes, while up to 70% of the drug is released within 3 minutes.

Pharmacokinetics:

With sublingual administration levomenthol absorbed from the oral mucosa, metabolized in the liver and excreted kidneys in the form of glucuronides.

Indications:

Functional cardialgia, neuroses, and also as an antiemetic for sea and air sickness.

Contraindications:Hypersensitivity to the components of the drug, age (under 18 years).

Pregnancy and lactation:

The purpose of the drug during pregnancy and breastfeeding is possible if the intended benefit to the mother exceeds the potential risk for fetus and child.

Dosing and Administration:Validol appoint adults for 1 capsule under the tongue until it is completely resorbed. Take 1 capsule 2-3 times a day. Multiplicity and duration of admission is determined depending on the effectiveness of treatment. In the absence or lack of expression of therapeutic effect in the coming 5-10 minutes after taking it, you need to see a doctor for another therapy.

Side effects:Nausea, lacrimation, dizziness; allergic reactions are possible.

Overdose:

Symptoms: headache, nausea, nervous state, disorder activity of the heart, a sharp decrease in blood pressure, suppression of the central nervous system.

Treatment: cancel the drug. Symptomatic therapy.

Interaction:

When used simultaneously with drugs that depress the central nervous system, enhances the effect of the latter.

The simultaneous use of Validol with nitrates reduces the headache that occurs when they are used.

Special instructions:

Effect on the ability to drive transp. cf. and fur:

When taking Validol, care must be taken when administering transport and other perspirationwith potentially dangerous species activities that require increased concentration of attention and speed of psychomotor reactions.

Form release / dosage:

Capsules sublingual for 50 mg or 100 mg.

Packaging:

For 50 capsules in a jar of polymer materials.

For 10 or 20 capsules in a contour mesh box made of a polyvinyl chloride film and aluminum foil.

To the bank or 1, 2, 4, 6 or 10 contour mesh packages together with the instruction for application put in a pack of cardboard for consumer packaging.

100, 200 or 400 contour mesh packages, together with an equal number of instructions for use, are placed in a bag of polyethylene film opaque.

Each package is placed in a box of cardboard box (for hospitals).

Storage conditions:

In a dry, dark place at a temperature of 5 to 25 ° C.

Keep out of the reach of children.

Shelf life:

2 years. Do not use after the expiration date.

Terms of leave from pharmacies:Without recipe

Registration number:LP-002992

Date of registration:12.05.2015

Expiration Date:12.05.2020

The owner of the registration certificate:MARBIOFARM, OJSC MARBIOFARM, OJSC Russia

Manufacturer: & nbsp

MARBIOFARM, OJSC Russia

Information update date: & nbsp18.01.2017

Illustrated instructions

Instructions

Validol (Validol)