Active substanceParacetamol + Phenylephrine + Pheniramine + Ascorbic acidParacetamol + Phenylephrine + Pheniramine + Ascorbic acid
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  • Dosage form: & nbsppowder for solution for oral administration [orange, lemon, raspberry]
    Composition:

    Per package:

    Active substances: phenylephrine hydrochloride 10 mg, phenyramine maleate 20 mg, ascorbic acid 50 mg, paracetamol 325 mg.

    Excipients:

    Powder for solution for oral administration [orange]: citric acid (citric acid anhydrous) 750.00 mg, malic acid 7.50 mg sucrose sugar 13599.17 mg titanium dioxide 2.20 mg sodium citrate sodium citrate anhydrous 123.00 mg, orange flavoring - 52,50 mg, dye quinoline yellow - 0,33 mg, calcium phosphate (tricalcium phosphate) - 60.00 mg, ethylcellulose - 0.30 mg;

    Powder for solution for oral administration [lemon]: citric acid (citric acid anhydrous) 750.00 mg, malic acid 7.50 mg, sucrose sugar 13599.17 mg titanium dioxide 2.20 mg sodium citrate sodium citrate anhydrous 123.00 mg, lemon flavoring - 52,50 mg, dye quinoline yellow - 0,33 mg, calcium phosphate (tricalcium phosphate) 60.00 mg, ethylcellulose - 0.30 mg;

    Powder for solution for oral administration [crimson]: citric acid (citric acid anhydrous) 750.00 mg, malic acid 7.50 mg, sucrose sugar 13599.17 mg titanium dioxide 2.20 mg sodium citrate sodium citrate anhydrous 123.00 mg, raspberry flavoring - 52,50 mg, quinoline yellow dye-0,083 mg, azorubin (acid red 2C) -0,247 mg, calcium phosphate (tricalcium phosphate) -60.00 mg, ethyl cellulose -0.30 mg.

    Description:

    Powder for solution for oral administration [orange]: granular powder of yellow color with a specific odor. It is allowed the presence of crystals and white granules and easily crumbling lumps. The powder is dissolved in 250 ml of hot water to form an opalescent solution of light yellow color with a characteristic orange odor.

    Powder for solution for oral administration [lemon]: granular powder of yellow color with a specific odor. It is allowed the presence of crystals and white granules and easily crumbling lumps. The powder is dissolved in 250 ml of hot water to form an opalescent solution of light yellow color with a characteristic smell of lemon.

    Powder for solution for oral administration [crimson]: granular powder from light pink to dark pink with a reddish tint of color with a specific smell. It is allowed the presence of crystals and white granules and easily crumbling lumps. The powder is dissolved in 250 ml of hot water to form an opalescent solution of pink color with a characteristic smell of raspberry.

    Pharmacotherapeutic group:Means for elimination of symptoms About IZ and "colds" (an anesthetic non-narcotic remedy + alpha-adrenomimetic + 111-gysgamine receptor blocker + vitamin)
    ATX: & nbsp

    N.02.B.E   Anilides

    N.02.B.E.51   Paracetamol in combination with other drugs, excluding psycholeptics

    Pharmacodynamics:Combined drug, has antipyretic, vasoconstrictive, analgesic and antiallergic effect. Paracetamol has antipyretic and analgesic effect: reduces the pain syndrome, which is observed in "cold" diseases - sore throat, headache, muscle and joint pain, reduces heat. Pheniramine has an anti-allergic effect: eliminates swelling and flushing mucous membranes of the nasal cavity, nasopharynx and paranasal sinuses, reduces runny nose and watery eyes. Phenylephrine has a vasoconstrictive effect: reduces swelling of the nasopharyngeal mucosa. Ascorbic acid (vitamin C) replenishes the increased need for vitamin C for colds and flu, especially at the initial stages of the disease; increases the body's resistance to infectious diseases. The combined action of phenyramine and phenylephrine leads to a reduction in nasal congestion and a significant relief of nasal breathing.
    Indications:Symptomatic treatment of "colds", colds, flu, accompanied by fever, chills, headache, runny nose, pain in the sinuses of the nose and throat, nasal congestion, sneezing and pain in the muscles and joints.
    Contraindications:Hypersensitivity to individual components of the drug, marked hepatic / renal failure, pregnancy, the period of breastfeeding, children's age (up to 12 years).
    Carefully:With arterial hypertension, diabetes, closed-angle glaucoma, liver or kidney disease, prostatic hyperplasia, deficiency of glucose-6-phosphate dehydrogenase.
    Pregnancy and lactation:The use of the drug during pregnancy is contraindicated. If it is necessary to use the drug during breastfeeding, breastfeeding should be discontinued.
    Dosing and Administration:Dissolve the contents of one packet in 1 glass of boiled hot water. To use in a hot kind. You can add sugar to taste. Repeated dose can be taken every 4 hours (no more than 3 doses in 24 hours). Maksikold® Rino from flu and cold can be used at any time of the day, but the best effect is taken by taking the drug before going to bed, at night. If there is no relief of symptoms within 3 days after starting the drug, you should see a doctor.
    Side effects:Possible allergic reactions, drowsiness, nausea, epigastric pain, dry mouth. paresis of accommodation, increased excitability, dizziness, increased blood pressure, falling asleep, urinary retention, rarely: anemia.
    Overdose:

    Symptoms: nausea, vomiting, pain in the epigastric region; hepatotoxic and nephrotoxic action, in severe cases, hepatic insufficiency, encephalopathy and coma.

    Treatment: should make a lavage of the stomach, take Activated carbon and see a doctor.

    Interaction:

    It is recommended to refrain from taking the drug when taking inhibitors of mopogminoxidase. The risk of hepatotoxic action of paracetamol increases with the simultaneous administration of barbiturates, diphenin, carbamazepine, rifampicin. zidovudine and other inducers of microsomal liver enzymes. Antidepressants, antiparkinsonian and antipsychotic drugs, phenosine derivatives increase the risk of urinary retention, dry mouth. constipation.

    Reduces the hypotensive effect of guanethidine, which in turn increases the alpha-adrenostimulating activity of phenylephrine.

    Special instructions:

    To avoid toxic damage to the liver paracetamol should not be combined with the reception of alcoholic beverages, but also to people prone to chronic alcohol consumption.

    The risk of liver damage increases in patients with alcoholic hepatosis.

    In case of taking the drug, patients suffering from diabetes or on a diet with a low sugar content, it should be taken into account that each packet contains 13599.17 mg of sugar, which corresponds to 1 XE.

    Do not use the drug from damaged packets.

    Effect on the ability to drive transp. cf. and fur:During the period of application of the drug it is not recommended to operate vehicles and various mechanisms, as well as carry out other potentially dangerous activities requiring increased attention and speed of mental and motor reactions.
    Form release / dosage:Powder for solution for oral administration [orange, lemon, raspberry] 15 g.
    Packaging:

    For 15.0 g of the preparation in a heat-sealable packet of combined material.

    For 5 or 10 packages with instructions for use in a pack of cardboard.

    Storage conditions:

    Store at a temperature not exceeding 25 ° C.

    Keep out of the reach of children.

    Shelf life:2 years. Do not use after expiry date.
    Terms of leave from pharmacies:Without recipe
    Registration number:LSR-000054
    Date of registration:26.04.2007 / 05.02.2016
    Expiration Date:Unlimited
    The owner of the registration certificate:OTISIFARM, OJSC OTISIFARM, OJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp29.03.2018
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