Active substanceParacetamol + Phenylephrine + Pheniramine + Ascorbic acidParacetamol + Phenylephrine + Pheniramine + Ascorbic acid Similar drugsTo uncover GrippoFlu® for cold and flu powder inwards MARBIOFARM, OJSC Russia Grippoflu® extra cold and flu powder inwards MARBIOFARM, OJSC Russia Asterisk Fly powder inwards Danson Trading Pharmaceutical Company Limited Vietnam Maxikold® Reno powder inwards OTISIFARM, OJSC Russia Stopgripan powder inwards Alvogen IPKo S.A.L. Luxembourg Stopgripan forte powder inwards Alvogen IPKo S.A.L. Luxembourg TeraFlu® against influenza and colds powder inwards Новартис Консьюмер Хелс СА Switzerland Dosage form: & nbspPowder for solution for ingestion (lemon, blackcurrant). Composition:Active substances:Paracetamol 650 mgPhenylephrine hydrochloride 10 mg Pheniramine maleate 20 mgAscorbic acid 50 mgExcipients: calcium phosphate, citric acid, maltodextrin, sodium citrate dihydrate, sucrose, titanium dioxide, ethyl maltol, malic acid;Lemon: Flavoring lemon, coloring sunny sunset yellow, dye quinoline yellow,Blackcurrant: Black-currant aroma, blue diamond dye, yellow sunset sunset, dye Ponso 4R. Description:Stoppgripte forte powder for solution for ingestion (lemon): Crystalline powder of light yellow color with a characteristic smell of lemon. Reconstituted solution: opaque yellowish liquid with lemon odor. Pharmacotherapeutic group:Remedy for elimination of symptoms of ARI and "colds" (analgesic non-narcotic means + alpha-adrenomimetic + H1-histamine receptor blocker + vitamin). ATX: & nbspN.02.B.E AnilidesN.02.B.E.51 Paracetamol in combination with other drugs, excluding psycholeptics Pharmacodynamics:Combined drug. Paracetamol has antipyretic and analgesic effect. Phenylephrine - vasoconstrictive action, thereby contributing to the elimination of edema of the mucous membranes of the nose, nasopharynx and paranasal sinuses, reducing the discharge from the nose, thereby facilitating nasal breathing. Pheniramine has antiallergic and anti-edematous effect, reduces vascular permeability, nasal discharge, lacrimation, eliminates sneezing. Ascorbic acid participates in the regulation of oxidation-reduction processes, carbohydrate metabolism,coagulability of blood, tissue regeneration, in the synthesis of steroid hormones; increases the body's resistance to infections, reduces vascular permeability, reduces the need for vitamins Bl, B2, A, E, folic acid, pantothenic acid. It improves paracetamol tolerance and lengthens its action. Indications:Catarrhal diseases, influenza, acute rhinitis, rhinopharyngitis, sinusitis, inflammation of the paranasal sinuses, accompanied by fever, chills, runny nose, a feeling of nasal congestion, headache. Pain syndrome (mild and moderate): arthralgia, myalgia, neuralgia, migraine, dental and headache, pain with trauma, algodismenorea. Contraindications:Hypersensitivity to paracetamol and other components that make up the drug; reception of other preparations containing substances that are part of Stopgripan. forte; simultaneous reception of tricyclic antidepressants, monoamine oxidase (MAO) inhibitors, beta-blockers; portal hypertension; alcoholism; diabetes; pregnancy, lactation; children's age till 15 years. Carefully:With severe arteriosclerosis of the coronary arteries, arterial hypertension, deficiency of glucose-6-phosphate dehydrogenase; blood diseases, congenital hyperbilirubinemia (Gilbert syndrome, Dubin-Johnson and Rotor syndrome), hepatic and / or renal insufficiency, closed-angle glaucoma, prostate adenoma; hyperthyroidism, pheochromocytoma, bronchial asthma. Dosing and Administration:Contents 1 sachet (sachet) pour into a glass, pour hot water, stir until completely dissolved and drink. Adults and children over 15 years: take one packet 3-4 times a day with intervals between meals 6 hours (no more than 4 bags per day). Consult your doctor if symptoms persist for 5 days. Side effects:In therapeutic doses, the drug is usually well tolerated, but there may be: increased blood pressure, allergic reactions (skin itch, rash, hives, angioedema), dry mouth, nausea, vomiting, epigastric pain, decreased rate of psychomotor reactions, increased excitability , dizziness, palpitations, sleep disturbances, urinary retention, renal colic, glucosuria, mydriasis, paresis of accommodation, increased intraocular pressure.Given the presence of paracetamol in the drug, rarely can there be violations of the hematopoiesis system (thrombocytopenia, leukopenia, agranulocytosis, hemolytic anemia, aplastic anemia); with long-term administration of high doses - there may be abnormalities on the part of the liver and kidneys (hepatotoxic effect, nephrotoxicity - papillary necrosis). Overdose:It is conditioned, as a rule, by paracetamol. Possible: pallor of the skin, anorexia, nausea, vomiting, pain in the epigastric region; in severe cases - hepatic insufficiency, hepatonecrosis, increased activity of "liver" transaminases, increased prothrombin time, encephalopathy and coma. A detailed clinical picture of liver damage manifests itself after 1-6 days. Rarely, hepatic insufficiency develops at a lightning speed and can be complicated by renal insufficiency (tubular necrosis).Treatment: gastric lavage followed by the administration of activated charcoal; symptomatic therapy; the introduction of donors of moieties of SH-groups and precursors of the synthesis of glutathione-methionine after 8-9 hours after an overdose and N-acetylcysteine - after 12 hours. Interaction:Strengthens the effects of MAO inhibitors, sedatives, ethanol.Antidepressants, anti-parkinsics, antipsychotics, phenothiazine derivatives - increase the risk of urinary retention, dry mouth, constipation. Glucocorticosteroids increase the risk of increased intraocular pressure.Paracetamol reduces the effectiveness of uricosuric drugs and improves the effectiveness of indirect anticoagulants.Phenyramin simultaneously with MAO inhibitors, furazolidone can lead to hypertensive crisis, agitation, hyperpyrexia. Tricyclic antidepressants enhance the sympathomimetic effect, the simultaneous administration of halothane increases the risk of ventricular arrhythmia. Reduces the hypotensive effect of guanethidine, which in turn increases the alpha-adrenostimulating activity of phenylephrine. With the simultaneous appointment of Stopgripan forte with barbiturates, diphenin, carbamazepine, rifampicin and other inducers of microsomal liver enzymes, the risk of hepatotoxic action of paracetamol increases. Special instructions:To avoid toxic damage to the liver, the drug should not be combined with the use of alcoholic beverages.If, despite the reception of Stoppippan forte, the disease is accompanied by continuing fever or there are repeated increases in temperature, it is necessary to see a doctor. Effect on the ability to drive transp. cf. and fur:Patients taking Stopgrypan forte should refrain from studies that require increased attention and speed of mental and motor reactions, including driving. Form release / dosage:Powder for solution for ingestion (lemon, blackcurrant). Packaging:By 21.5 grams of powder in a sachet of aluminum foil and laminated paper. For 10 sachets together with instructions for use in a pack of cardboard. Storage conditions:In a dry place at a temperature of no higher than 25 ° C.Keep out of the reach of children. Shelf life:3 years. Do not use after the expiration date printed on the package. Terms of leave from pharmacies:Without recipe Registration number:LSR-000835/08 Date of registration:18.02.2008 / 19.08.2013 Expiration Date:Unlimited The owner of the registration certificate:Alvogen IPKo S.A.L.Alvogen IPKo S.A.L. Luxembourg Manufacturer: & nbspRUSAN PHARMA, Ltd. India Representation: & nbspAlvogen Pharma Trading EuropeAlvogen Pharma Trading Europe Information update date: & nbsp2016-12-19 Illustrated instructions × Illustrated instructions Instructions