Pikamilon - instructions for use, dose, side effects, contraindications

Nootropic agent, dilates the vessels of the brain. Has a tranquilizing and mild psycho-stimulating effect, antiplatelet and antioxidant effect. Improves the functional state of the brain by normalizing tissue metabolism and affecting cerebral circulation (increases the volumeand linear speed of cerebral blood flow, has vasodilator, antiplatelet, antioxidant effect, improves microcirculation). At the course reception increases physical and mental efficiency, reduces headache, improves memory, normalizes sleep; contributes to the reduction or disappearance of feelings of anxiety, tension, fear, emotional incontinence. Promotes the restoration of central motor and speech disorders of vascular or traumatic origin. Improves blood circulation in the vessels of the retina and optic nerve.

Pharmacokinetics:Absorption is fast and complete in any way of administration. It penetrates the blood-brain barrier, it is retained for a long time in the tissues of the body. Bioavailability is 50-88%. It is excreted mainly by the kidneys in unchanged form. The half-life is 0.51 hours.

Indications:

Adults:

- chronic cerebrovascular insufficiency (dyscirculatory encephalopathy, consequences of cerebral circulation disorders), condition after traumatic brain injury, vegetative dystonia syndrome, as a part of complex therapy of depressive disorders of various genesis in old age.

- in the complex treatment for chronic alcoholism (reduction of asthenic, asthenoneurotic, postpsychotic, pre-recurrent conditions with alcoholic encephalopathy).

- in the complex therapy of primary open-angle glaucoma with compensated intraocular pressure (to stabilize the visual function).

- in the complex therapy of the syndrome of vegetative dystonia, accompanied by anxiety, fear, increased irritability, asthenia, emotional lability.

- to improve the tolerance of physical and mental loads, to increase the resistance to stress (for persons in tense and extreme conditions of activity, to restore the physical performance of athletes, to increase resistance to physical and mental stress).

Children over 3 years and adults in urological practice in disorders of urination to improve the adaptive function of the bladder (reduction in detrusor hypoxia).

Contraindications:Hypersensitivity, chronic renal failure, pregnancy, lactation, children under 3 years (in children over 3 years of age it is used in disorders of urination).

Carefully:

Pregnancy and lactation:contraindicated

Dosing and Administration:

Intravenous drip or jet (slow), intramuscularly.

Before drip introduction, the contents of the ampoule are dissolved in 200 ml of 0.9% sodium chloride solution.

In chronic cerebrovascular insufficiency: injected 100-200 mg once a day for 10 days intravenously, then intramuscularly. A course of treatment 15-30 days. When the condition improves, they switch to oral forms in a daily dose of 50-150 mg. The second course is in 5-6 months.

As part of complex therapy in the treatment of depressed elderly: 50-200 mg per day for 10-15 days.

In the treatment of chronic alcoholism, 100 mg per day is administered with a course of 6-15 days.

To restore efficiency at high loads, 200 mg are administered in a daily dose of 10-15 days, for athletes - at the same dose within 14 days of the training period.

In the complex therapy of the syndrome of vegetative dystonia appoint 100-200 mg for 10-15 days.

In the complex treatment of primary open-angle glaucoma, 100-200 mg per day is administered for 10 days.

In the treatment of disorders of urination: intramuscularly administered 100 mg (for children from 3 to 10 years), 200 mg per day (for children over 11 years and adults).

Side effects:

Reduced blood pressure, dizziness, headache, mild nausea, irritability, agitation, anxiety, allergic reactions (skin rash, itching).

Overdose:

Increased severity of dose-dependent symptoms of side effects. Treatment is symptomatic.

Interaction:Shortens the action of barbiturates, enhances the action of narcotic analgesics.

Special instructions:

Effect on the ability to drive transp. cf. and fur:Perhaps the negative effect of the drug on the performance of potentially hazardous activities requiring special attention and speed of response (driving, working with moving mechanisms, etc.).

Form release / dosage:

Solution for intravenous and intramuscular injection 50 mg / ml and 100 mg / ml.

For 2 ml in ampoules from neutral glass grade HC-1A or HC-3 or imported.

10 ampoules per box of cardboard. 10 ampoules per contour cell pack of a polyvinylchloride film and aluminum foil or 5 ampoules into a contoured cell pack of a polyethylene terephthalate film without foil.

1 circuit cell pack of 10 ampoules or 2 contour packs of 5 ampoules are placed in a pack of cardboard.

In the box and the pack, the instructions for use and the scarifier are put (when packing ampoules with notches, rings and fracture points, scarifiers do not invest).

Packaging:solution for intravenous and intramuscular injection, 50 mg / ml, 100 mg / ml (ampoule) 2 ml x 5/10 (cardboard pack)

Storage conditions:

In the dark place at a temperature of no higher than 25 C.

Keep out of the reach of children.

Shelf life:

3 years.

Do not use after the expiration date indicated on the package.

Terms of leave from pharmacies:On prescription

Registration number:LS-001744

Date of registration:27.07.2010

The owner of the registration certificate:PHARMSTANDART-UFIM VITAMIN FACTORY, OJSC PHARMSTANDART-UFIM VITAMIN FACTORY, OJSC Russia

Manufacturer: & nbsp

PHARMSTANDART-UFIM VITAMIN FACTORY, OJSC Russia

Information update date: & nbsp11.08.2015

Illustrated instructions

Instructions

Pikamil® (Pikamilon®)