Pikamilon - instructions for use, dose, side effects, contraindications

Nootropic agent, dilates the vessels of the brain. It also has a tranquilizing, psycho-stimulating, anti-aggregative and antioxidant effect. Improves the functional state of the brain due to the normalization of tissue metabolism and effects on cerebral circulation (increases the volume and linear speed of the brainblood flow, reduces the resistance of cerebral vessels, inhibits platelet aggregation, improves microcirculation).

At the course reception increases physical and mental efficiency, reduces headache, improves memory, normalizes sleep; contributes to the reduction or disappearance of feelings of anxiety, tension, fear; improves the condition of patients with motor and speech disorders.

Pharmacokinetics:It penetrates the blood-brain barrier, it is retained for a long time in the tissues of the body. Bioavailability - 50-88 %. It is excreted mainly by the kidneys in an unchanged form. The half-life period is 0.51 hours.

Indications:

Cerebrovascular insufficiency, asthenia, depressive disorders in old age.

Conditions, accompanied by anxiety, fear, increased irritability, emotional lability. Asthenic conditions caused by various neuropsychic diseases.

As part of a comprehensive treatment - for the management of acute alcohol intoxication; with chronic alcoholism - to reduce asthenic, asthenoneurotic, postpsychotic, pre-recurrent conditions, as well as alcoholic encephalopathy.In the complex therapy - migraine (prevention), TBI, neuroinfection. Improving the portability of physical and mental loads (to persons who are in tense and extreme conditions of activity, to restore the physical performance of athletes, to increase resistance to physical and mental stress).

Open angle glaucoma (to stabilize the visual function).

In urological practice (in children older than 3 years and in adults with disorders of urination) to improve the adaptive function of the bladder (reducing detoxification hypoxia).

Contraindications:

Hypersensitivity, chronic renal failure, pregnancy and lactation.

Pregnancy and lactation:contraindicated

Dosing and Administration:

Intramuscularly, intravenously (drip or jet slowly). Before the drip introduction, the contents of the ampoule are dissolved in 200 ml of 0.9% sodium chloride.

For chronic disorders of cerebral circulation - intravenously or intramuscularly, 0.1-0.2 g, 1-2 times a day, at a daily dose of 0.2-0.4 g. Depending on the patient's condition, morning intravenous drip is prescribed, intramuscularly in the evening; or 10 days intravenously, then intramuscularly.The course of treatment is 15-30 days.

In asthenic conditions, depending on the severity of the disease, picamilone is prescribed intramuscularly in a daily dose of 0.2-0.4 g (2-4 ml of a solution of 100 mg / ml). Duration of treatment - 1 month.

For the treatment of acute uncomplicated intoxication with the standard, Pikamilon, as part of complex therapy, is administered at a saturating dose of 5 mg / kg and maintaining -1.56 mg / kg / h in a volume of 2.5 liters of the infusion solution for 4 hours in the morning and in the evening.

For the treatment of chronic alcoholism, the drug is used in a daily dose of 0.6-0.8 g. The course of treatment is 1 month.

Side effects:

Allergic reactions (skin rash, itching), dizziness, headache, mild nausea, irritability, anxiety.

With rapid intravenous injection - hyperemia of the face, paresthesia.

Overdose:

Increased severity of symptoms of side effects.

Treatment is symptomatic.

Interaction:Shortens the time of action of barbiturates, intensifies the action of narcotic analgesics.

Special instructions:

Effect on the ability to drive transp. cf. and fur:

Form release / dosage:

Solution for intravenous and intramuscular injection 100 mg / ml. Ampoules of 2 ml.

For 10 ampoules with a knife ampoule or scarifier ampoule and instructions for use in a box of cardboard.

For 5 or 10 ampoules in a contour cell package.

For 1 or 2 contour squares with instructions for use and a knife for opening ampoules or a scarifier ampoule in a pack of cardboard.

When packaging ampoules with a break ring or break point, the ampoule opener or ampoule scarifier may not be inserted.

Packaging:(1) - ampoule (10) / complete with a knife ampoule or scarifier, if necessary for ampoules of this type / - cardboard boxes
(1) - ampoules (10) / complete with a knife ampoule or scarifier, if necessary for ampoules of this type / - packaging contour plastic (pallets)
(1) - ampoules (5) / complete with a knife ampoule or scarifier, if necessary for ampoules of this type / - packaging contour plastic (pallets)

Storage conditions:

List B. Store in a dark place at a temperature of 5 to 25 ° C.

Keep out of the reach of children.

Shelf life:

3 years. Do not use after the expiration date.

Terms of leave from pharmacies:On prescription

Registration number:P N002858 / 01

Date of registration:29.08.2008

The owner of the registration certificate:NOVOSIBHIMFARM, OJSC NOVOSIBHIMFARM, OJSC Russia

Manufacturer: & nbsp

NOVOSIBHIMFARM, OJSC Russia

Information update date: & nbsp13.08.2015

Illustrated instructions

Instructions

Picalon (Pikamilon)