Structum - instructions for use, doses, side effects, contraindications

Gelatin capsules from light blue to blue. The contents of the capsules are a whitish-cream powder, conglomerates (lumps) are allowed, connected with the features of the spatial structure.

The size of capsules No. 1 (for 250 mg) and No. 0 (for 500 mg).

Pharmacotherapeutic group:Reparation of tissue stimulant.

ATX: & nbsp

M.01.A.X Other non-steroidal anti-inflammatory drugs

Pharmacodynamics:It affects the metabolic processes in hyaline and fibrous cartilage, reduces degenerative changes in the cartilaginous tissue of the joints, stimulates the biosynthesis of glycosaminoglycans. Slows the resorption of bone tissue and reduces calcium loss, accelerates the recovery of bone tissue. When treated with Structum, soreness decreases and mobility of affected joints improves. The therapeutic effect persists for a long time after the end of the course of treatment.

Pharmacokinetics:More than 70% of chondroitin sulfate is absorbed in the digestive tract. Bioavailability of the drug is 13%. With a single admission of the medial therapeutic dose, the maximum concentration in the plasma is noted after 3-4 hours, in the synovial fluid after 4-5 hours. Absorbed in the GIT, the drug accumulates in the synovial fluid. It is excreted by the kidneys.

Indications:Osteoarthritis, intervertebral osteochondrosis.

Contraindications:

- Hypersensitivity to the components of the drug;

- Children under 15 years of age (due to lack of accurate data).

Pregnancy and lactation:Structum is not recommended during pregnancy and lactation due to the lack of sufficient clinical data.

Dosing and Administration:Inside, washing down with water. Adults and adolescents with 15 years of age appoint 1 g per day - 2 capsules 250 mg or 1 capsule 500 mg 2 times a day. The recommended duration of the initial course of treatment is 6 months, the period of the drug after its withdrawal is 3-5 months depending on the location and stage of the disease, the duration of repeated courses of treatment is established by the doctor.

Side effects:Rarely: allergic reactions (hives, erythema, skin itching); nausea, vomiting.

Overdose:In rare cases, symptoms of an overdose on the part of the gastrointestinal tract are possible: nausea, vomiting, diarrhea; with prolonged intake of excessively high doses (over 3 g / day), hemorrhagic eruptions are possible. Treatment is symptomatic.

Interaction:With the simultaneous use of Structum with other drugs, the effect of indirect anticoagulants, antiaggregants, fibrinelitics may be increased.

Special instructions:Caution should be given to patients with bleeding, as well as patients with a tendency to bleeding.

Form release / dosage:

Capsules 250 mg and 500 mg.

Packaging:

Capsules 500 mg

1. For 12 capsules in a blister of PVC and aluminum foil, 5 blisters each, along with instructions for use in a pack of cardboard.

2. For 20 capsules in a blister of PVC and aluminum foil; on 3,4, 5, 6, 7 or 10 blisters together with instructions for use in a pack of cardboard.

Capsules 250 mg

For 15 capsules in a blister of PVC and aluminum foil, 4 blisters together with instructions for use in a pack of cardboard.

Storage conditions:At a temperature not higher than 25 ° C. Keep out of the reach of children.

Shelf life:

3 years.

Do not use the drug after the expiration date.

Terms of leave from pharmacies:Without recipe

Registration number:П N013685 / 01

Date of registration:06.07.2007

The owner of the registration certificate:Pierre Fabre Medication ProductionPierre Fabre Medication Production France

Manufacturer: & nbsp

PIERRE FABRE MEDICAMENT PRODUCTION France

Representation: & nbspPIER FABR PIER FABR France

Information update date: & nbsp07.10.2015

Illustrated instructions

Instructions

Structum® (Structum®)