Active substanceGlucosamine + chondroitin sulfateGlucosamine + chondroitin sulfate
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  • Dosage form: & nbspGel for external use.
    Composition:

    Active substances: chondroitin sodium sulfate 5.0 g, glucosamine sodium sulfate chloride (in terms of glucosamine sulfate) 2.5 g.

    Excipients: sodium disulfite (sodium metabisulphite) 0.05 g, ethanol 96% (rectified ethyl alcohol 96%) 25.0 g, propylene glycol 10.0 g, carbomer (carbopol) 3.0 g, methyl parahydroxybenzoate (nipagine, methylparaben ) - 0.2 g, lavender oil - 0.05 g, purified water - up to 100 g.

    Description:Colorless or yellowish shade gel with a specific odor.
    Pharmacotherapeutic group:Reparation of tissue stimulant.
    ATX: & nbsp

    M.01.A.X   Other non-steroidal anti-inflammatory drugs

    Pharmacodynamics:
    Stimulates the regeneration of cartilaginous tissue, has anti-inflammatory and analgesic effect. Glucosamine and chondroitin sulfate participate in the synthesis of connective tissue, contributing to the prevention of cartilage destruction processes and stimulating the regeneration of tissue.
    Glucosamine has chondroprotective properties, takes part in the biosynthesis of proteoglycans and hyaluronic acid. Glucosamine selectively acts on the articular cartilage, is a specific substrate and stimulator of the synthesis of hyaluronic acid and proteoglycans, inhibits the formation of peroxide radicals and enzymes that damage the cartilaginous tissue (collagenase and phospholipase).
    Chondroitin sulfate stimulates the formation of articular cartilage components, the synthesis of proteoglycans and type II collagen, and also protects hyaluron from enzymatic cleavage (by suppressing the activity of hyaluronidase) and the damaging effect of free radicals. Chondroitin sulfate maintains the viscosity of the synovial fluid, stimulates mechanisms of cartilage repair and suppresses the activity of those enzymes (elastase, hyaluronidase), which split the cartilage. Chondroitin sulfate in the treatment of osteoarthritis facilitates the symptoms of this disease and reduces the need for non-steroidal anti-inflammatory drugs (NSAIDs).
    Indications:Osteoarthrosis (including joints and spine I-III st.).
    Contraindications:Increased individual sensitivity to the components of the drug, damage to the integrity of the skin at the site of application, children under 18 years of age, pregnancy, lactation.
    Pregnancy and lactation:During pregnancy and during breastfeeding (lactation), the drug is not used.
    Dosing and Administration:Outwardly. The gel is applied 2-3 times a day with a thin layer of 4 cm (2 g) strip on intact skin over the lesion site, then rubbed until absorbed for 2-3 minutes. Duration of the drug - 1 month. A repetition of the course is possible.
    Side effects:
    Allergic reactions.
    If you notice any other side effects not listed in the instructions, tell your doctor.
    Overdose:No data available.
    Interaction:No data available.
    Special instructions:
    For external use only.The drug should be applied only to intact skin areas, avoiding contact with open wounds, eyes and mucous membranes.


    Effect on the ability to drive transp. cf. and fur:The drug has no effect on the ability to drive vehicles, mechanisms and engage in other hazardous activities requiring special attention and quick reactions.
    Form release / dosage:
    Gel for external use 5,0 g + 2,5 g.
    Packaging:
    30 grams, 50 grams, 100 grams of aluminum tubes. 30 grams, 50 grams, 100 grams in laminated tubes with screwed polymer bushon. Each tube with instructions for medical use in a pack of cardboard.

    Storage conditions:
    In the dark place at a temperature of no higher than 25 C. Do not freeze. Keep out of the reach of children.
    Shelf life:
    3 years. Do not use the product after the expiry date printed on the package.
    Terms of leave from pharmacies:Without recipe
    Registration number:LP-000043
    Date of registration:28.03.2013
    Date of cancellation:2015-11-18
    The owner of the registration certificate:SYNTHESIS, OJSC SYNTHESIS, OJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp29.09.2015
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