Aquacitramone - instructions for use, dose, side effects, contraindications

Acetylsalicylic acid has analgesic, antipyretic and anti-inflammatory action, inhibits platelet aggregation. Paracetamol has antipyretic, analgesic effect. Caffeine reduces drowsiness and fatigue, increases mental and physical performance, increases heart rate, increases blood pressure in hypotension.

Pharmacokinetics:

Indications:

Aquacitramone is used in adults with mild to moderate pain syndrome (headache, toothache, neuralgia, myalgia, thoracic radicular syndrome, lumbago, arthralgia, menstruation pain, etc.), in adults and children over 15 years of age to reduce fever, at "cold" and other infectious-inflammatory diseases.

Contraindications:

Increased individual sensitivity to the components of the drug, erosive ulcerative lesions (in the exacerbation phase) of the gastrointestinal tract, gastrointestinal bleeding, increased tendency to bleeding, "aspirin asthma", " hemorrhagic diathesis (hemophilia, disease Willebrand, telangiectasia, hypoprothrombinemia, thrombocytopenia, thrombocytopenic purpura),exfoliating aortic aneurysm, portal hypertension. Deficiency of vitamin K. Deficiency of glucose-6-phosphate dehydrogenase. Pregnancy (I and III trimester) and the period of breastfeeding.

The drug is not prescribed as an anesthetic for people under 18 years old, as an antipyretic agent - children under 15 years with acute respiratory diseases caused by viral infections, because of the danger of developing Reye's syndrome (encephalopathy and acute fatty liver disease with acute development of liver failure) .

Carefully:Diperuricemia, urate nephrolithiasis, padagra, peptic ulcer and / or duodenal ulcer (in the anamnesis), decompensated heart failure.

Pregnancy and lactation:Acetylsalicylic acid has a teratogenic effect: when applied in the first trimester of pregnancy leads to malformations - the cleavage of the upper palate; at III trimester - inhibition of labor (inhibition of the synthesis of prostaglandins), the closure of the arterial duct in the fetus, which causes hyperplasia of the pulmonary vessels and hypertension in the vessels of the small circulation. Acetylsalicylic acid is excreted in breast milk, which increases the risk of bleeding in the child due to impaired platelet function.

Dosing and Administration:

One packet of the drug is dissolved in 100 ml of water and drunk. Allowed a slight deposit in the glass. Use a freshly prepared solution.

The drug is used inside after eating 1 packet 2-3 times a day. The maximum daily dose is 6 packs. The interval between doses should be at least 4 hours.

If there is a violation of the kidney or liver function, the break between doses is not less than 6 hours.

The drug should not be taken more than 5 days with an appointment as an anesthetic and more than 3 days as an antipyretic. Other dosages and regimens are prescribed by the doctor.

Side effects:

Anorexia, nausea, vomiting, gastralgia, diarrhea, erosive-ulcerative lesions of the gastrointestinal tract, gastrointestinal bleeding, hepatic and / or renal insufficiency, increased blood pressure, tachycardia. Allergic reactions: skin rash, Quincke's edema, bronchospasm.

With prolonged admission - dizziness, headache, visual impairment, tinnitus,reduction of platelet aggregation, hypocoagulation, hemorrhagic syndrome (epistaxis, bleeding gums, purpura, etc.), renal damage with papillary necrosis; deafness; Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell syndrome), Reye's syndrome in children (hyperpyrexia, metabolic acidosis, disorders of the nervous system and psyche, vomiting, liver dysfunction).

Overdose:

Nausea, vomiting, pain in the stomach, sweating, pallor of the skin, tachycardia. With light intoxication - ringing in the ears; severe intoxication - incoherent thinking, drowsiness, collapse, convulsions, bronchospasm, shortness of breath, anuria, bleeding. As the intoxication intensifies, progressive respiratory paralysis and dissociation of oxidative phosphorylation causing respiratory acidosis.

If you suspect a poisoning, you should immediately seek medical help.

Treatment: the affected person should rinse the stomach and prescribe adsorbents (Activated carbon).

Interaction:

Enhances the effect of heparin, oral anticoagulants, reserpine, steroid hormones and hypoglycemic agents.Reduces the effectiveness of spironolactone, furosemide, antihypertensive drugs, anti-arthritis agents that promote the excretion of uric acid.

Enhances side effects of glucocorticosteroids, derivatives sulfonylureas, methotrexate, non-narcotic analgesics and non-steroidal anti-inflammatory drugs.

Avoid combination of the drug with barbiturates, antiepileptics, zidovudine, rifampicin and alcohol-containing beverages (the risk of hepatotoxic effect increases).

Under the influence of paracetamol, the time of chloramphenicol elimination is increased by 5 times. Caffeine accelerates the absorption of ergotamine.

Special instructions:

With continued use of the drug, control of peripheral blood and the functional state of the liver is necessary. Because the acetylsalicylic acid has an antiaggregatory effect, the patient, if he is to undergo surgery, should warn the doctor in advance about taking the drug. Acetylsalicylic acid in low doses reduces the excretion of uric acid. This can in some cases provoke a gout attack.

During treatment, you should stop using alcohol-containing beverages (increased risk of gastrointestinal bleeding).

Form release / dosage:Granules for solution for oral administration.

Packaging:

3 grams of granules in a single-dose, contiguous, non-jammed package (package).

For 5 or 10 packs together with instructions for use in the pack.

Storage conditions:

In a dry, the dark place at a temperature of no higher than + 25 ° C, inaccessible to children.

Shelf life:

2 years. Do not use after the expiration date printed on the package.

Terms of leave from pharmacies:Without recipe

Registration number:P N003404 / 01

Date of registration:29.12.2009

Expiration Date:Unlimited

The owner of the registration certificate:Akvatsitramon, OOOAkvatsitramon, OOO

Manufacturer: & nbsp

ROSFARM, LLC Russia

Information update date: & nbsp24.06.2017

Illustrated instructions

Instructions

Aquacitramone (Aquacitramon)