Citrapar - instructions for use, doses, side effects, contraindications

Active substances: Acetylsalicylic acid (in recalculation on a 100% substance) - 240 mg; Paracetamol (in terms of 100% ve180 mg; Caffeine (in terms of 100% substance) - 30 mg.

Excipients: Citric acid - 20 mg, povidone (polyvinylpyrrolidone) 3.0 mg, talc 14.0 mg, silicon dioxide colloid (aerosil) 3.0 mg.

Weight of the contents of the capsule: 490.0 mg

Composition of the capsule: titanium dioxide, gelatin, dye sunset yellow (E 110), dye crimson [Ponso 4R] (E 124).

Description:

Hard gelatin capsules of white and orange color No. 0 (white capsule body, orange lid). The contents of the capsules are white or white powder with a cream or pink shade of color.

Pharmacotherapeutic group:analgesic agent combined (NSAIDs + analgesic non-narcotic remedy + psychostimulant)

ATX: & nbsp

N.02.B.A.51 Acetylsalicylic acid in combination with other drugs, excluding psycholeptics

Pharmacodynamics:

Combined drug with analgesic, antipyretic, anti-inflammatory and tonic acting. Due to the content of acetylsalicylic acid reduces the ability of platelets to aggregate (formation of thrombi).

Indications:

Applied with a moderate or mild pain syndrome (headache, toothache, joint pain, neuralgia, myalgia, dysmenorrhea and others), can also be used to reduce elevated body temperature with colds and other infectious and inflammatory diseases.

The expediency of using the drug as an antipyretic agent is decided in each case depending on the severity, nature and tolerability of the fever.

Contraindications:

Increased individual sensitivity to the components of the drug. Peptic ulcer disease of the stomach and duodenum, gastrointestinal bleeding, pronounced impaired liver or kidney function. Genetic absence of glucose-6-phosphate dehydrogenase. Diseases of the blood with a tendency to hemorrhage and bleeding.Glaucoma, bronchial asthma. Portal hypertension, marked arterial hypertension (contains caffeine).

The first three months of pregnancy and the period of breastfeeding. The drug is not prescribed for children under 15 years with acute respiratory infections caused by viral infections (acute respiratory viral infection, influenza) because of the risk of development of Ray's syndrome.

Dosing and Administration:

Usually the drug is taken one capsule 2-3 times a day after meals, washed down with water or milk. The maximum daily dose is 4 capsules.

In case of violations of the kidney or liver function, the interval between doses should be at least 8 hours.

The drug should not be taken for more than five days as an anesthetic and for more than three days as an antipyretic without prescription and supervision by a doctor. Other dosages and schedules are prescribed by the doctor.

Side effects:

Sometimes skin allergic reactions (rash, itching, urticaria), pain in the stomach, nausea, vomiting, increased blood pressure, palpitations, bronchospasm are possible. With prolonged use in high doses, there may be violations of the liver and kidney function, erosive and ulcerative lesions of the gastrointestinal tract.About any side (unusual) the effects of the drug, including those not listed in this leaflet should be reported to your doctor.

Overdose:

Signs of acute poisoning - nausea, vomiting, stomach pain, sweating, pale skin, tachycardia. If you suspect a poisoning, you should immediately seek medical help.

Treatment: the gastric lavage should be done using activated charcoal.

Interaction:

The drug enhances the effect of reducing blood clotting agents and platelet aggregation, as well as side effects of glucocorticoids, sulfonylureas, methotrexate, non-narcotic analgesics and non-steroidal anti-inflammatory agents.

Reduces the effectiveness of spironolactone, furosemide, antihypertensive drugs, as well as protivopodagricakih medicaments promoting excretion of uric acid.

Barbiturates, rifampicin, salicylamide, Antiepileptic agents lekarstveenye and other stimulants microsomal oxidation contribute to the formation of toxic metabolites of paracetamol affecting the liver function. Metoclopromide accelerates the absorption of paracetamol.

Under the influence of paracetamol, the excretion of chloramphenicol increases five-fold. At repeated reception paracetamol can enhance the effect of anticoagulants (derivatives of dicumarin). Simultaneous reception of paracetamol and ethanol increases the risk of hepatotoxic effects.

Caffeine accelerates the absorption of ergotamine.

Special instructions:

With caution apply in the elderly, patients with impaired liver or kidney function.

Use of other medicines should be agreed with the doctor. Because the acetylsalicylic acid slows the clotting of the blood, the patient, if he is to undergo surgery, must warn the doctor in advance about taking the drug.

Acetylsalicylic acid in low doses reduces the excretion of uric acid. In patients with a corresponding predisposition, this can in some cases provoke a gout attack.

During treatment should be abandoned the use of ethanol (increased risk of gastrointestinal bleeding).

Form release / dosage:

Capsules.

Packaging:

10 capsules per contour cell package.

For 10 or 20 capsules in cans of polymeric with screw caps.

The bank or 1,2 contour mesh packages together with the instruction for use are placed in a pack of cardboard.

Storage conditions:

In a dry, the dark place at a temperature of no higher than 30 ° C. Keep out of the reach of children.

Shelf life:3 years. Do not use after the expiry date printed on the package.

Terms of leave from pharmacies:Without recipe

Registration number:P N000961 / 01

Date of registration:14.08.2008/06.06.2014

The owner of the registration certificate:BRYNTSALOV-A, CJSC BRYNTSALOV-A, CJSC Russia

Manufacturer: & nbsp

BRYNTSALOV-A, CJSC Russia

Information update date: & nbsp16.06.2016

Illustrated instructions

Instructions

Citrapar® (Citrapak® )