From the side of the cardiovascular system, palpitations, dyspnea, marked decrease in blood pressure, fainting, vasculitis, peripheral edema (swelling of the ankles and feet), "tides" of blood to the skin of the face, rarely - rhythm disturbances (bradycardia, ventricular tachycardia, atrial flutter), myocardial infarction, chest pain , orthostatic hypotension, very rarely - development or aggravation of heart failure, extrasystole, migraine.
From the central nervous system: headache, dizziness, fatigue, drowsiness, mood lability, convulsions, rarely - loss of consciousness, hypoesthesia, peripheral neuropathy, paresthesia, tremor, vertigo, asthenia, malaise, insomnia, depression, unusual dreams, very rarely - ataxia, apathy, agitation, amnesia.
From the digestive system: nausea, vomiting, epigastric pain, rarely - increased activity of "liver" transaminases and jaundice (caused by cholestasis), pancreatitis, dry mouth, thirst, hepatitis, flatulence, gingival hyperplasia,constipation or diarrhea, very rarely - gastritis, increased appetite, anorexia, hyperbilirubinemia.
From the genitourinary system: rarely - pollakiuria, painful urge to urinate, nocturia, violation of sexual function (including a decrease in potency); very rarely - dysuria, polyuria.
From the skin: very rarely - xeroderma, alopecia, dermatitis, purpura, a violation of skin pigmentation.
Allergic reactions: pruritus, rash (including erythematous, maculopapular rash, urticaria), angioedema, erythema multiforme.
From the musculoskeletal system: rarely - arthralgia, arthrosis, muscle cramps, myalgia (with prolonged use); very rarely - myasthenia gravis.
Other: rarely - gynecomastia, hyperuricemia, increase / decrease in body weight, thrombocytopenia, leukopenia, hyperglycemia, impaired vision, diplopia, conjunctivitis, eye pain, ringing in the ears, back pain, dyspnoea, epistaxis, increased sweating, thirst; very rarely - cold sticky sweat, cough, rhinitis, parosmia, taste disorders, accommodation disorder, xerophthalmia.