From the cardiovascular system: palpitation, dyspnea, marked decrease in blood pressure, fainting,vasculitis, edema (swelling of the ankles and feet), "tides" - blood to the face, rarely - arrhythmias (bradycardia, ventricular tachycardia, atrial flutter), chest pain, orthostatic hypotension, very rarely - the development or exacerbation of congestive heart failure, arrythmia , migraine.
From the central nervous system: headache, dizziness, fatigue, drowsiness, mood changes, seizures, rare - loss of consciousness, hypoesthesia, nervousness, paresthesia, tremor, vertigo, fatigue, malaise, insomnia, depression, abnormal dreams, very rarely - ataxia, apathy, agitation, amnesia.
From the digestive system: nausea, vomiting, epigastric pain, rarely - increased level of "liver" transaminases and jaundice (caused by cholestasis), pancreatitis, dry mouth, flatulence, gingival hyperplasia, constipation or diarrhea, rarely - gastritis, increased appetite, anorexia, hyperbilirubinemia, hepatitis.
From the genitourinary system: rarely - pollakiuria, painful urge to urinate, nocturia, violation of sexual function (including a decrease in potency); very rarely - dysuria, polyuria.
From the hematopoiesis: very rarely - thrombocytopenic purpura, leukopenia, thrombocytopenia.
From the respiratory system: rarely shortness of breath, rhinitis; very rarely - cough.
From the skin: very rarely - xeroderma, alopecia, dermatitis, discoloration of the skin.
Allergic reactions: skin itch, rash (including erythematous, maculopapular rash), very rarely - angioedema, erythema multiforme, urticaria.
From the musculoskeletal system: rarely - arthralgia, arthrosis, myalgia (with prolonged use); very rarely - myasthenia gravis.
Other: rarely - gynecomastia, polyuricemia, weight gain / decrease, hyperglycemia, visual impairment, diplopia, conjunctivitis, eye pain, ringing in the ears, back pain, epistaxis, increased sweating, thirst; rarely - cold sticky sweat, parosmia, a violation of taste sensations, a violation of accommodation, xerophthalmia.