Do not use Biosulin ® 30/70, if after shaking the suspension does not turn white and evenly cloudy.
On the background of insulin therapy, continuous monitoring of blood glucose levels is necessary.
Causes hypoglycemia In addition to an overdose of insulin, there may be: drug substitution, skipping meals, vomiting, diarrhea, increased physical activity, diseases that reduce the need for insulin (liver and kidney dysfunction, hypofunction of the adrenal cortex, pituitary gland or thyroid gland), injection site change, and interaction with other drugs.
Incorrect dosing or breaks in the administration of insulin, especially in patients with type 1 diabetes, can lead to hyperglycemia. Usually the first symptoms of hyperglycemia develop gradually, over a period of several hours or days. They include the appearance of thirst, increased urination, nausea, vomiting, dizziness, redness and dryness of the skin, dry mouth, loss of appetite, odor of acetone in the exhaled air. If not treated, hyperglycemia in type 1 diabetes can lead to the development of life-threatening diabetic ketoacidosis. The dose of insulin must be corrected in case of thyroid dysfunction, Addison's disease, hypopituitarism, liver and kidney dysfunction and diabetes mellitus in persons over 65 years of age.
Correction of the dose of insulin may also be required if the patient increases the intensity of physical activity or changes the habitual diet.
Concomitant diseases, especially infections and conditions accompanied by fever, increase the need for insulin.
The transition from one type of insulin to another should be carried out under the control of blood glucose.
The drug lowers tolerance to alcohol.
Due to the possibility of precipitation in some catheters, the use of the drug in insulin pumps is not recommended.
Instructions to be given to the patient
The technique of injection with the use of insulin in vials
If the patient uses only one type of insulin
1. Disinfect the rubber membrane on the vial.
2. Put the air in the syringe in the amount corresponding to the required dose of insulin. Insert air into the vial with insulin.
3. Turn the bottle with the syringe upside down and type the desired dose of insulin into the syringe. Remove the needle from the vial and remove air from the syringe. Check the correctness of the dose of insulin.
4. Immediately inject.
If the patient needs to mix two types of insulin
1. Disinfect the rubber membranes on the vials.
2. Just before the set, take a bottle of long-acting insulin ("cloudy") between the palms until the insulin becomes evenly white and cloudy.
3. Type in the syringe air in an amount corresponding to the dose of "turbid" insulin. Enter the air into the bottle with a "cloudy" insulin and remove the needle from the bottle.
4. Type in the syringe air in an amount corresponding to a dose of insulin of short action ("transparent"). Insert air into the bottle with "transparent" insulin. Turn the bottle with the syringe upside down and type the desired dose of "transparent" insulin. Remove the needle and remove air from the syringe. Check the correctness of the dialed dose.
5. Insert the needle into the bottle with a "cloudy" insulin, flip the bottle with the syringe upside down and type the desired dose of insulin. Remove air from the syringe and check the correctness of the dialed dose. Immediately inject the dialed mixture of insulin.
6. Always take the insulin in the same sequence described above.
The technique of injection with the use of insulin in cartridges
The cartridge with the preparation Biosulin ® 30/70 is intended for use only with the syringe handle Biosulin ® Pen.The patient should be warned about the need to carefully follow the instructions in the instructions for using the syringe pen for insulin administration.
Before use, make sure that there are no damages (for example, cracks) on the cartridge with Biosulin® 30/70. Do not use the cartridge if there are any visible damage. After the cartridge is inserted into the syringe pen, a colored strip should be visible through the cartridge holder window.
Before placing the cartridge in the syringe pen, turn the cartridge up and down so that the glass ball moves from end to end of the cartridge. This procedure should be repeated at least 10 times, until all the liquid becomes white and evenly turbid. Immediately after this, an injection must be made.
If the cartridge is already inside the pen syringe, turn it with the cartridge inside up and down at least 10 times. This procedure must be repeated before each injection.
After the injection, the needle should remain under the skin for a minimum of 6 seconds. Keep the button depressed until the needle is completely removed from the skin, thus ensuring the correct dose administration and limiting the possibility of blood or lymph flow into the needle or the insulin cartridge.
The cartridge with the preparation Biosulin® 30/70 is intended only for individual use and can not be refilled.
Injection procedure
- With two fingers, take the fold of the skin, insert the needle into the base of the fold at an angle of about 45 ° and insert insulin under the skin.
- After the injection, the needle should remain under the skin for at least 6 seconds, in order to ensure that the insulin is injected completely.
- If blood is removed from the needle after the needle is removed, gently press the injection site with your finger.
- It is necessary to change the injection site.