Doppelgerz Vitamin E forte (DOPPELHERZ VITAMINE E FORTE)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceVitamin EVitamin E
Dosage form: & nbspcapsules
Composition:

1 capsule

Active components:

RRR-a-tocopheryl acetate concentrate-182.00 mg (RRR -a-tocopheryl acetate-147 mg = 200 ME soybean oil-35 mg)

Excipients: soybean oil - 88.00 mg

Weight of the contents of the capsule is 270.00 mg

Capsule shell composition:

gelatin 84.22 mg, glycerol 23.45 mg, sorbitol 70% solution (not crystallizable) 11.14 mg, water purified 71.19 mg.

Capsule shell weight - 190.00 mg

Weight capsule with contents - 460.00 mg

Description:

Soft gelatinous oval-shaped capsules containing a yellow, oily liquid, odorless.

Pharmacotherapeutic group:Vitamin.
ATX: & nbsp

A.11.H.A.03   Tocopherol (vitamin E)

Pharmacodynamics:

Vegetable vitamin E. Has an antioxidant effect. Protects the cellular membranes of body tissues from oxidative changes; stimulates the synthesis of gem and heme-containing enzymes - hemoglobin, myoglobin, cytochromes, catalase, peroxidase. It inhibits the oxidation of unsaturated fatty acids. Inhibits the synthesis of cholesterol, promotes the normalization of lipid levels in blood plasma, prevents increased permeability of capillaries. Reduces clotting of blood, participates in tissue respiration and other processes of tissue metabolism. Vitamin E is necessary for the normal development and functioning of the gonads.Participates in the biosynthesis of collagen, gemma and proteins, activates the proliferation of cells.

Indications:

Hypovitaminosis of vitamin E;

-increased physical and mental loads;

- in the complex therapy of peri- and postmenopausal disorders;

-degenerative and proliferative changes in the joints, ligamentous apparatus of the spine and muscles.

-astenic conditions, including in old age.

Contraindications:

Hypersensitivity to the components of the drug, acute myocardial infarction, children under 18 years.

Carefully:

Use in patients with severe cardiosclerosis who underwent myocardial infarction, with an increased risk of thromboembolism; hypoprothrombinemia caused by vitamin K deficiency.

Pregnancy and lactation:

During pregnancy and during breastfeeding, the drug is prescribed in an average daily dose for adults under the supervision of a doctor.

Dosing and Administration:

Vitamin E is taken after a meal, without chewing, with a small amount of liquid washed down with 1 capsule per day; in other cases, the drug is prescribed on the recommendation of a doctor.

With degenerative and proliferative changes in the joints, ligamentous apparatus of the spine and muscles - 1 capsule per day.

In the case of hypovitaminosis - for adults, a single median dose is 1 capsule per day, the maximum dose is 2 capsules per day.

Duration of the course on the recommendation of a doctor.

Side effects:

Allergic reactions (itching, skin hyperemia).

Overdose:

When taking vitamin E for a long period in doses of 400-800 IU / day - blurred vision, dizziness, headache, nausea, severe fatigue, diarrhea, gastralgia, asthenia.

When taking more than 800 IU / day for a long period - an increased risk of bleeding in patients with hypovitaminosis K, a disorder of thyroid hormone metabolism, a disorder of sexual function, thrombophlebitis, thromboembolism, necrotic colitis, sepsis, renal failure, bleeding in the retina, hemorrhagic stroke, ascites.

Treatment: symptomatic, withdrawal of the drug, the appointment of glucocorticosteroids.

Interaction:

Iron preparations are recommended to be used 8-12 hours before or after taking Doppelgerz® Vitamin E forte (impaired absorption of iron ions).

Taking very high doses of vitamin E can increase the effect of indirect anticoagulants.

With simultaneous reception of indirect anticoagulants and vitamin E, it is necessary to regularly monitor blood coagulability.

Strengthens the effect of glucocorticosteroids, nonsteroidal anti-inflammatory drugs, antioxidants.

Vitamin E in high doses can cause vitamin A deficiency in the body. Increases the effectiveness of antiepileptic drugs in patients with epilepsy (who have increased blood levels of products of lipid peroxidation).

Colestramine, colestipol, mineral oils reduce the absorption of vitamin E.

Special instructions:

It is necessary to strictly follow the dosing regimen.

With long-term use of the drug and / or the need to prescribe repeated courses of therapy, it is recommended to periodically monitor blood coagulation indicators, as well as the level of cholesterol in the blood.

Form release / dosage:

Capsules 200 ME.

Packaging:
For 20 capsules in a blister of PVC and Al-foil. For 3 or 5 blisters with instructions for use are placed in a cardboard box.
Storage conditions:

Store at a temperature not exceeding 25 ° C.

Keep out of the reach of children!

Shelf life:

4 years.

Do not use after expiry date.

Terms of leave from pharmacies:Without recipe
Registration number:П N013258 / 01
Date of registration:07.07.2008
The owner of the registration certificate:Kvasser Pharma GmbH & Co. KGKvasser Pharma GmbH & Co. KG Germany
Manufacturer: & nbsp
Representation: & nbspKvayser Pharma LLCKvayser Pharma LLCRussia
Information update date: & nbsp30.07.2015
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