Active substanceHemicellulase + Bile components + PancreatinHemicellulase + Bile components + Pancreatin Similar drugsTo uncover Biofestal pills inwards BIOFARMA, CJSC Russia Normoenzyme pills inwards PHARMSTANDART-FORESTRY, OJSC Russia Normoenzyme forte pills inwards PHARMSTANDART-FORESTRY, OJSC Russia Ferestal® pills inwards BRYNTSALOV-A, CJSC Russia Festal® pills inwards Sanofi India Limited India Enzistal® pills inwards Torrent Pharmaceuticals Co., Ltd. India Dosage form: & nbspenteric coated tablets Composition:Each tablet contains: Active substances: Pancreatin 192.00 mg (protease activity: not less than 300 units. MFF, lipase activity: not less than 6000 U. MFF, amylase activity: not less than 4500 units MFF), bovine bile extract 25,00 mg, hemicellulase 50, 00 mg.Excipients: lactose monohydrate 67.30 mg, magnesium stearate 4.00 mg, silicon colloidal dioxide 1.70 mg,Intestinal soluble coat: cellulose 21.61 mg. diethyl phthalate 3.89 mg, Sugar shell: sucrose 114.209 mg, calcium carbonate 67.73 mg, talc 33.369 mg, acacia gum 4.278 mg, gelatin 4.278 mg, titanium dioxide 0.422 mg, beeswax yellow 0,114 mg. Description:White, round biconvex tablets, covered with sugar shell. Pharmacotherapeutic group:digestive enzyme ATX: & nbspA.09.A.A Enzyme preparations Pharmacodynamics:Combined drug, the effect of which is due to the components that make up its composition. Enzistal® has a protective coating that does not dissolve until it enters the small intestine, which protects the enzymes from the destructive effect of gastric juice. Enzistal® promotes fast and complete digestion of food, facilitates the symptoms resulting from digestive disorders (a feeling of heaviness and overfilling of the stomach, flatulence, shortness of breath due to the accumulation of gases in the intestines, diarrhea).Enzymes included in pancreatin - amylase, lipase and protease - facilitate the digestion of carbohydrates, fats and proteins, which contributes to their fuller absorption in the small intestine.Hemicellulase is an enzyme that promotes the breakdown of plant fiber, which also improves digestive processes, reduces the formation of gases in the intestine.Bile extract acts cholagogically, promotes fat emulsification, increases lipase activity, improves absorption of fats and fat-soluble vitamins A, D, E, K. Indications:- To improve digestion in individuals with normal gastrointestinal function in the case ofinaccuracies in nutrition (irregular / unhealthy diet, eating fatty foods, overeating);- In case of violation of the chewing function, forced long-term immobilization, sedentary lifestyle;- Insufficiency of the exocrine function of the pancreas (chronic pancreatitis, cystic fibrosis);- Chronic inflammatory-dystrophic diseases of the stomach, intestines, liver, gall bladder; conditions after resection or irradiation of these organs, accompanied by disruption of food digestion, flatulence, diarrhea (as part of combination therapy);- Preparation for X-ray and ultrasound examination of the abdominal organs. Contraindications:Hypersensitivity to the drug components, acute pancreatitis, exacerbation of chronic pancreatitis, hepatic insufficiency, hepatitis, mechanical jaundice, cholelithiasis, gallbladder empyema, intestinal obstruction, children under 6 years old, cholelithiasis. Carefully:cystic fibrosis. Pregnancy and lactation:During pregnancy and lactation, the drug is prescribed only if the expected benefit to the mother exceeds the potential risk to the fetus or child. Dosing and Administration:Enzistal® is taken orally, without chewing, during or immediately after eating, with a small amount of liquid.Adults - 1-2 tablets 3 times a day. Higher doses are prescribed by the doctor. Children older than 6 years (as prescribed by a doctor) - 1 tablet 2-3 times a day. The duration of treatment can vary from several days (if the digestive process is disturbed due to inaccuracies in the diet) to several months or years (if necessary, permanent replacement therapy).Before x-ray or ultrasound examination - 2 tablets 2-3 times a day for 2-3 days before the test. Side effects:Allergic reactions, nausea, diarrhea, abdominal pain, decreased endogenous synthesis of bile acids. With prolonged use in high doses, it is possible to develop hyperuricosuria, an increase in the level of uric acid in the blood plasma.At children at application of high doses development of perianal irritation and irritation of a mucous membrane of an oral cavity is possible. Overdose:Symptoms: hyperuricemia and hyperuricuria.Treatment: withdrawal of the drug, symptomatic therapy. Interaction:With simultaneous application with Enzistal®, absorption of PASK, sulfonamides, antibiotics is enhanced; it is possible to reduce the absorption of iron preparations. Simultaneous use of antacid agents containing calcium carbonate and / or magnesium hydroxide, can lead to a decrease in the effectiveness of Enzistal®. Cimetidine enhances the effect of the drug. Special instructions:In cystic fibrosis, the drug should be administered with caution, because The dose should be adequate to the quantity and quality of the food consumed. Form release / dosage:Tablets, covered with enteric coating. Packaging:10 tablets in Al / Al. blister. 2, 4 or 8 blisters of 10 tablets with instructions for use are packed in a cardboard box. Storage conditions:Store at a temperature of no higher than 25 ° C in a dry, protected from light place.Keep out of the reach of children. Shelf life:3 years. Do not use after the expiry date printed on the package. Terms of leave from pharmacies:Without recipe Registration number:П N015075 / 01 Date of registration:24.04.2009 The owner of the registration certificate:Torrent Pharmaceuticals Co., Ltd.Torrent Pharmaceuticals Co., Ltd. India Manufacturer: & nbspTORRENT PHARMACEUTICALS, Ltd. India Representation: & nbspTORRENT PHARMACEUTICALS LTD. TORRENT PHARMACEUTICALS LTD. India Information update date: & nbsp2015-12-12 Illustrated instructions × Illustrated instructions Instructions