Active substanceHemicellulase + Bile components + PancreatinHemicellulase + Bile components + Pancreatin Similar drugsTo uncover Biofestal pills inwards BIOFARMA, CJSC Russia Normoenzyme pills inwards PHARMSTANDART-FORESTRY, OJSC Russia Normoenzyme forte pills inwards PHARMSTANDART-FORESTRY, OJSC Russia Ferestal® pills inwards BRYNTSALOV-A, CJSC Russia Festal® pills inwards Sanofi India Limited India Enzistal® pills inwards Torrent Pharmaceuticals Co., Ltd. India Dosage form: & nbspdragees are enteric. Composition:Kernel composition Active substances:Pancreatin - 192 mg equivalent (amylase - 4,500 FIP U lipase - 6000 FIP U protease - 300 FIP U);Hemicellulase - 50 mg;Bile components - 25 mg;Excipients: sodium chlorideShell compositionExcipients: tsellatsefat (cellulose acetate phthalate), ethyl vanillin, castor oil, sucrose, methyl parahydroxybenzoate (methyl paraben), propyl parahydroxybenzoate (propylparaben), gelatin, dextrose liquid (glucose liquid), talc, calcium carbonate, acacia gum, glycerol (glycerine), mahfogol ( polyethylene glycol 6000), titanium dioxide. Description:White, glossy, round pills with low odor of vanilla. Pharmacotherapeutic group:digestive enzyme ATX: & nbspA.09.A.A Enzyme preparations Pharmacodynamics:The drug compensates for the lack of exocrine function of the pancreas due to pancreatin, and the bile excretory function of the liver due to the bile component. Festal has a proteolytic, amylolytic and lipoidic effect. Enzymes included in pancreatin: amylase, lipase and protease facilitate digestion of carbohydrates, fats and proteins, which contributes to their fuller absorption in the small intestine. And in this respect Festal practically does not differ from other enzyme preparations.The presence of bile acids in Festal gives the drug additional options for correcting biliary insufficiency, which often accompanies chronic pancreatitis. The bile extract acts cholagogically, facilitates the absorption of fats and fat-soluble vitamins A, E and K, promotes the release of lipase by the pancreasEnzyme hemicellulase promotes the cleavage of plant fiber, which also improves digestive processes, reduces the formation of gases in the intestine. Indications:Insufficiency of the exocrine function of the pancreas in chronic pancreatitis in combination with biliaryinsufficiency due to various pathological conditions, clinically manifested by disturbances in food digestion, flatulence, propensity to constipation, as part of combination therapy with:- diffuse liver diseases - alcohol and toxic liver damage, liver cirrhosis;- large losses of bile acids (in patients after cholecystectomy);- disturbance of bile acid circulation, observed during dyskinesia of bile ducts, dysbacteriosis, malabsorption;- Violation of the neurohumoral regulation of the processes of bile formation and bile secretion in chronic diseases of the gastrointestinal tract-chronic gastritis, chronic duodenitis, chronic cholecystitis;To improve the digestion of food in patients with normal function of the gastrointestinal tract in the case of errors in nutrition, as well as violations of the masticatory function, forced long-term immobilization, sedentary lifestyle.Preparation for X-ray and ultrasound examination of the abdominal organs. Contraindications:Hypersensitivity to the components of the drug, acute pancreatitis, exacerbation of chronic pancreatitis,hepatic insufficiency, hepatic coma or precoma, hepatitis, hyperbilirubinemia, jaundice, cholelithiasis, empyema of the gall, bladder, bowel obstruction, susceptibility to diarrhea, children under 3 years (for a given dosage form). Carefully:cystic fibrosis, pregnancy. Dosing and Administration:Inside.The drug is taken orally, without chewing, during or immediately after eating, with a small amount of liquid.Assign 1-2 drops 3 times a day. Higher doses are prescribed only by a doctor. Dosage and dosing regimen in children is determined by the doctor.The duration of treatment can vary from several days (if the digestive process is disturbed due to inaccuracies in the diet) to several months or years (if necessary, permanent replacement therapy).Before x-ray or ultrasound examination - 2 tablets 2-3 times a day 2-3 days before the test. Side effects:Allergic reactions (redness of the skin, sneezing, watery eyes), nausea, diarrhea, abdominal pain (including intestinal colic). With prolonged use in high doses, it is possible to develop hyperuricemia, hyperuricuria.Children (when taken in large doses) may develop perianal irritation and irritation of the mucous membrane of the oral cavity. Overdose:Symptoms of overdose are hyperuricemia and hyperuricuria. When there are symptoms of overdose - withdrawal of the drug and symptomatic therapy. Interaction:With simultaneous application with Festal, the absorption of PASK (p-aminosalicylic acid), sulfonamides, antibiotics is enhanced; it is possible to reduce the absorption of iron preparations. The simultaneous use of antacid agents containing calcium carbonate and / or magnesium hydroxide, can lead to a decrease in Festal's effectiveness. Cimetidine enhances the effect of the drug. Form release / dosage:The dragees are enteric-soluble. Packaging:10 tablets in an aluminum strip. By 2. 4, 6 or 10 strips together with instructions for use in a cardboard pack. Storage conditions:Store at a temperature of no higher than 25 ° C in a dry place.Keep out of the reach of children. Shelf life:3 years.Do not use after the expiration date printed on the package. Terms of leave from pharmacies:Without recipe Registration number:П N014796 / 01 Date of registration:22.07.2008 The owner of the registration certificate:Sanofi India LimitedSanofi India Limited India Manufacturer: & nbspSANOFI INDIA, Limited India Representation: & nbspSanofi Aventis GroupSanofi Aventis Group Information update date: & nbsp2015-12-12 Illustrated instructions × Illustrated instructions Instructions