Included in the formulation
АТХ:A.09.A.A Enzyme preparations
Pharmacodynamics:Combined drug.
Hemicellulase
Promotes the breakdown of plant fiber, which reduces the formation of gases in the intestines and improves the digestive process.
Bile Bile Extract
It has choleretic effect, improves absorption of fats and fat-soluble vitamins, promotes emulsification of fats, increases lipase activity.
Pancreatin
Due to the enzymes (amylases, lipases and proteases) that make up pancreatin, it facilitates the digestion of carbohydrates and proteins, contributing to their full absorption in the small intestine.
Pharmacokinetics:
Not described.
Indications:
It is used for the treatment of chronic inflammatory-dystrophic diseases of the gallbladder, liver, intestines and stomach.It is used as part of complex therapy for conditions after resection or irradiation of the digestive system, if the external secretory function of the pancreas is insufficient (cystic fibrosis, chronic pancreatitis).
IV.E70-E90.E84 Cystic fibrosis
XI.K20-K31.K29 Gastritis and duodenitis
XI.K70-K77.K70 Alcoholic liver disease
XI.K70-K77.K71 Toxic liver disease
XI.K70-K77.K73 Chronic hepatitis, not elsewhere classified
XI.K80-K87.K81.1 Chronic cholecystitis
XI.K80-K87.K86.1 Other chronic pancreatitis
XI.K90-K93.K91.2 Disruption of absorption after surgery, not elsewhere classified
XI.K90-K93.K91.5 Postcholecystectomy syndrome
Contraindications:
Mechanical jaundice, acute hepatitis, obturation intestinal obstruction, acute or chronic pancreatitis in the acute stage, individual intolerance, children under 3 years old.
Carefully:
Diabetes mellitus (the composition of the drug includes glucose and sucrose).
Pregnancy and lactation:
Recommendations for FDA - category is not defined. It is used in pregnancy and lactation in cases where the expected effect exceeds the risk for the fetus and the baby.
Dosing and Administration:Inside for 1 dragee during or after each meal.The duration of treatment varies from several days to months and years (with the use of the drug for replacement therapy).
Side effects:Nausea, diarrhea, abdominal pain, allergic reactions.
Overdose:
Pains of a coliform character, skin irritation around the anus, lachrymation, skin hyperemia.
Treatment - lowering the dose or canceling the drug.
Interaction:Increases absorption para-aminosalicylic acid, fat-soluble vitamins, antibiotics and sulfonamides.
Reduces the bioavailability of iron preparations.
The simultaneous use of antacid agents containing calcium carbonate and / or magnesium hydroxide, leads to a decrease in the effectiveness of the drug.
Special instructions:
In cystic fibrosis, the dose of the drug should be adequate to the quality and quantity of food consumed.