Active substanceHemicellulase + Bile components + PancreatinHemicellulase + Bile components + Pancreatin Similar drugsTo uncover Biofestal pills inwards BIOFARMA, CJSC Russia Normoenzyme pills inwards PHARMSTANDART-FORESTRY, OJSC Russia Normoenzyme forte pills inwards PHARMSTANDART-FORESTRY, OJSC Russia Ferestal® pills inwards BRYNTSALOV-A, CJSC Russia Festal® pills inwards Sanofi India Limited India Enzistal® pills inwards Torrent Pharmaceuticals Co., Ltd. India Dosage form: & nbspIntestinal-coated tablets Composition:Each tablet contains as active substances:pancreatin - 0,192-0,210 g, which corresponds to the content of amylase - 4500 ED FIP, lipase - 6000 ED FIP, protease - 300 units FIP; hemicellulases - 0.050 g; extract of bovine bile - 0.025 g.Excipients: sodium chloride, acetylphthalylcellulose, titanium dioxide, castor oil, sucrose (sugar), methylparaben (nipagin), propylparaben (nipazole), gelatin, gum arabicum, calcium carbonate, liquid glucose, ethylvaniline, talc. Description:Round, biconvex tablets with a smooth glossy surface of white or almost white color. View of the break: the core is brownish-beige with dark and light impregnations and a characteristic odor of pancreatin. Pharmacotherapeutic group:digestive enzyme ATX: & nbspA.09.A.A Enzyme preparations Pharmacodynamics:The drug compensates for the inadequacy of the secretory function of the pancreas and the bile excretory function of the liver.Enzymes of amylase, lipase and protease, included in pancreatin, facilitate the digestion of carbohydrates, fats and proteins, which contributes to their more complete absorption in the small intestine.Enzyme hemicellulosa promotes the cleavage of plant fiber, which also improves digestive processes, reduces the formation of gases in the intestine.The bile extract acts cholagogically, facilitates the digestion of fats, promotes the release of lipase by the pancreas. Indications:Insufficiency of the exocrine function of the pancreas (with chronic pancreatitis, cystic fibrosis, etc.).Chronic inflammatory-dystrophic diseases of the stomach, intestines, liver, gall bladder; state after resection or irradiation of these organs, accompanied by disruption of food digestion, flatulence, diarrhea (as part of combination therapy).To improve the digestion of food in patients with normal gastrointestinal function in the case oferrors in nutrition, as well as violations of masticatory function, forced long-term immobilization, sedentary lifestyle.Preparation for X-ray and ultrasound examinations of the abdominal cavity organs. Contraindications:Hypersensitivity to the drug components, acute pancreatitis, exacerbation of chronic pancreatitis, hepatic insufficiency, hepatitis, mechanical jaundice, empyema of the gallbladder, intestinal obstruction. Carefully:In cystic fibrosis, the drug should be administered with caution, since the dose should be adequate to the quantity and quality of the food consumed. Pregnancy and lactation:In pregnancy and breast-feeding the drug is prescribed only in case of emergency. Dosing and Administration:The drug is taken orally, without chewing, during or immediately after eating, with a small amount of liquid.Adults - 1-2 tablets 3 times a day. Higher doses are prescribed by the doctor.Children - as prescribed by the doctor.Duration of treatment can vary from several days (if the digestive process is disturbed due to inaccuracy in the diet) to several months or years (if necessary, permanent replacement therapy).Before x-ray or ultrasound examination - 2 tablets 2-3 times a day for 2-3 days before the study. Side effects:Allergic reactions, diarrhea, nausea, abdominal pain, decreased endogenous synthesis of bile acids. With prolonged use in high doses, it is possible to develop hyperuricosuria, an increase in the level of uric acid in the blood plasma.In children with high-to application, the development of perianal irritation and irritation of the mucous membrane of the oral cavity is possible. Interaction:With simultaneous application with Ferestal®, absorption of PASK, sulfonamides, antibiotics is enhanced; it is possible to reduce the absorption of iron preparations. The simultaneous use of antacid agents containing calcium carbonate and / or magnesium hydroxide, can lead to a decrease in the effectiveness of Ferestal®. Form release / dosage:Tablets, covered with enteric-dissolvable coating. Packaging:For 10, 20, 30, 50, 60, 80, 100 tablets in the package. Storage conditions:List B. In a dry, protected from light, out of reach of children, at a temperature of no higher than 25 ° C. Shelf life:3 years.Do not use after the time specified on the package. Terms of leave from pharmacies:Without recipe Registration number:P N000716 / 01-2001 Date of registration:01.08.2008 The owner of the registration certificate:BRYNTSALOV-A, CJSC BRYNTSALOV-A, CJSC Russia Manufacturer: & nbspBRYNTSALOV-A, CJSC Russia Information update date: & nbsp2015-12-12 Illustrated instructions × Illustrated instructions Instructions