Active substanceFurazidineFurazidine
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  • Dosage form: & nbspPowder for solution for local and external use
    Composition:

    one sachet contains:

    active substance: potassium furozidine (furagin soluble) -100.0 mg [furazidine (furagin), potassium carbonate]

    auxiliary substance: sodium chloride - 900.0 mg

    Description:

    orangeish-brown color coarse powder

    Pharmacotherapeutic group:antimicrobial agent (nitrofuran derivative)
    ATX: & nbsp

    D.08.A.F   Nitrofuran derivatives

    J.01.X.E   Nitrofuran derivatives

    Pharmacodynamics:

    Antimicrobial agent, a derivative of nitrofuran. Effective against gram-positive cocci (Staphylococcus spp., Streptococcus spp.), Gram-negative rods (E. coli, Salmonella spp., Shigella spp., Klebsiella spp.). Stable Plasmodium aeruginosa, Enterococcus spp., Acinetobacter spp., most strains Proteus spp., Serratia spp. The mechanism of action is related to the inhibition of the synthesis of nucleic acids. Depending on the concentration has a bactericidal or bacteriostatic effect.

    Against most bacteria, the bacteriostatic concentration is 10-20 μg / ml. The bactericidal concentration is approximately 2 times higher. Under the influence of nitrofurans in microorganisms, the activity of the respiratory chain and the cycle of tricarboxylic acids (Krebs cycle) is suppressed, as well as the inhibition of other biochemical processes, which leads to the destruction of their membrane or cytoplasmic membrane. Nitrofurans increase the complement titer and the ability of leukocytes to phagocytose microorganisms.

    Indications:

    Furasol is used as a local remedy for the complex treatment of infectious and inflammatory diseases of the oral cavity, oropharynx, small wounds with the threat of infection, such as abrasions, scratches, small cuts and bruises, cracks, light burns.

    Contraindications:

    Hypersensitivity to furazidine or preparations of the nitrofuran series.

    Allergic dermatitis.

    Pregnancy and lactation.

    Do not use for children under 4 years old.

    Dosing and Administration:DFor local and external use.

    The solution is prepared immediately before use.

    Locally: the contents of the sachet are dissolved in 200 ml of hot boiled water and a warm solution is used to rinse the oral cavity and the oropharynx 2-3 times a day.

    Outwardly: the contents of the sachet are dissolved in 200 ml of hot boiled water and a warm solution is used to wash small wounds 1-2 times a day.

    Duration of treatment is 3-5 days.

    Side effects:

    Classification of undesirable side reactions by frequency of development:

    Very frequent (> 10%), frequent (> 1%, but <10%), infrequent (> 0.1% but <1%), rare (> 0.01% but <0.1%), very rare (<0.01%) is not known (can not be determined from 1 available data).

    Violations from the immune system: it is not known - allergic reactions (urticaria, pruritus, rash, allergic dermatitis).

    In this case, the drug is discontinued. Prescribe symptomatic therapy.

    In case of unusual reactions, consult a doctor about the advisability of further use of the drug.

    Overdose:

    The drug is low toxicity. Cases of overdose are not described.

    Interaction:

    In combination with antibiotics shows a synergy.

    In the case of drinking alcohol during treatment with the drug, the probability of developing skin allergic reactions increases.

    Special instructions:
    The solution is prepared immediately before use. Prepared solution should not be stored.

    Effect on the ability to drive transp. cf. and fur:Does not affect the ability to manage vehicles and mechanisms.
    Form release / dosage:

    For 1 g of the drug in a bag of laminate.


    Packaging:For 15 bags of laminate together with the instructions for use are placed in a pack of cardboard.
    Storage conditions:
    In a dry, the dark place at a temperature of 15 ° C to 25 ° C. Keep out of the reach of children.
    Shelf life:5 years. Do not use after the expiration date.
    Terms of leave from pharmacies:Without recipe
    Registration number:LSR-001976/07
    Date of registration:07.08.2007
    The owner of the registration certificate:Olainfarm, AOOlainfarm, AO Latvia
    Manufacturer: & nbsp
    Representation: & nbspOLAINFARM JSC OLAINFARM JSC Latvia
    Information update date: & nbsp12.11.2015
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