Possible side effects of the drug Indomethacin 50 Berlin-Chemie are listed below in the descending frequency of occurrence: often (≥ 1/100, <1/10), infrequently (≥ 1/1000, <1/100), rarely (≥ 1/10000, <1/1000), very rarely (<1/10000), including individual messages.
Disorders from the gastrointestinal tract:
Often: NSAID-gastropathy, abdominal pain, nausea, vomiting, anorexia, diarrhea, heartburn, dysfunction of the liver (increase in blood concentrations of bilirubin, "liver" transaminases), ulcerative stomatitis, exacerbation of colitis.
Rarely: gastritis.
With prolonged use in large doses - ulceration of the mucous membrane of the gastrointestinal tract.
Disturbances from the nervous system:
Often: headache.
Often: dizziness, drowsiness, fatigue, fatigue, irritability, depression.
Infrequently: peripheral neuropathy, muscle weakness, convulsions, agitation, insomnia.
Impaired sensory organs:
Often: noise in the ears, diplopia, corneal opacity, blurred vision, conjunctivitis, taste disorder.
Infrequently: hearing loss.
Disorders from the cardiovascular system:
Rarely: heart failure, tachyarrhythmia, increased blood pressure, edematous syndrome.
Disorders from the kidneys and urinary tract:
Infrequently: peripheral edema (especially in patients with hypertension or renal insufficiency).
Rarely: interstitial nephritis, nephrotic syndrome, papillary necrosis, impaired renal function, proteinuria, hematuria.
Violations from the blood and lymphatic system:
Rarely: bleeding (gastrointestinal, gingival, uterine, hemorrhoidal), anemia (including hemolytic and aplastic), leukopenia, agranulocytosis, eosinophilia, thrombocytopenia, thrombocytopenic purpura.
Disturbances from the skin and subcutaneous tissues:
Rarely: skin rash, itching, urticaria, angioedema, bronchospasm; in isolated cases - toxic epidermal necrolysis (Lyell's syndrome), erythema nodosum, anaphylactic shock, photosensitivity.
Laboratory indicators:
Glucosuria, hyperkalemia, hyperglycemia.
Local Reactions:
Burning, itching, heaviness in the anorectal area, exacerbation of hemorrhoids.
Other:
Aseptic meningitis (more often in patients with autoimmune diseases), increased sweating.